Results 91 to 100 of about 1,636,579 (314)

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Fredrik Barth: Ethnic Groups and Boundaries

open access: yesTidsskrift for Professionsstudier, 2022
John Matthias Gulløv
doaj   +1 more source

CHILDREN SOMATOTYPE STUDY OF DIFFERENT ETHNIC GROUPS FROM PLOVDIV REGION, BULGARIA [PDF]

open access: yesJournal of IMAB
The purpose of the present study was to determine and compare the children's somatotypes of three ethnic groups living in the Plovdiv region, Bulgaria. Material and Methods: A cohort of 194 children were enrolled in the study.
Atanas Baltadjiev   +6 more
doaj   +1 more source

Ectopic cardiovascular fat in middle-aged men: effects of race/ethnicity, overall and central adiposity. The ERA JUMP study. [PDF]

open access: yes, 2015
Background/objectivesHigher volumes of ectopic cardiovascular fat (ECF) are associated with greater risk of coronary heart disease (CHD). Identifying factors that are associated with ECF volumes may lead to new preventive efforts to reduce risk of CHD ...
Barinas-Mitchell, E   +17 more
core   +2 more sources

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

A comparison of skeletal, dentoalveolar and soft tissue characteristics in white and black Brazilian subjects

open access: yesJournal of Applied Oral Science, 2010
OBJECTIVE: This study aimed to compare skeletal, dentoalveolar and soft tissue characteristics in white and black Brazilian subjects presenting normal occlusions.
Lívia Maria Andrade de Freitas   +4 more
doaj   +1 more source

Scale-Invariant Measures of Segregation [PDF]

open access: yes
We characterize measures of school segregation for any number of ethnic groups using a set of purely ordinal axioms that includes Scale Invariance: a school district?s segregation ranking should be invariant to changes that do not a¤ect the distribution ...
David M. Frankel, Oscar Volij
core  

Improving Blood Donor Diversity Through Focused Recruitment Interventions [PDF]

open access: yes, 2017
Study Design: Beginning in May 2016, the Jefferson Blood Donor Center began collecting donor self-identified race/ethnicity: White, Black or African American, Hispanic, Asian or Pacific Islander, American Indian or Alaskan Native, Multiracial, Other ...
Amanullah, Sarah   +3 more
core   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

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