Results 121 to 130 of about 1,651,799 (309)

[Review of] Frank J. Cavaioli and Salvatore J. LaGumina. The Peripheral Americans [PDF]

open access: yes, 1986
This book is primarily a discussion of foreign ethnic groups who have come to the United States. Perhaps the most striking thing about it is that it is a revision of The Ethnic Dimension in American Society (Holbrook Press, Boston, 1974) with the authors\
Davies, Phillips G.
core   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

[Review of] Leonard Dinnerstein, Roger L. Nichols, and David M. Reimers Natives and Strangers: Ethnic Groups and the Building of America [PDF]

open access: yes, 1980
Although the past decade has witnessed a surge in the number of publications focusing on ethnic groups and ethnic issues, the genre of study which may be called “ethnic history of America”‘ is still weakly represented.
Parming, Tönu
core   +2 more sources

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Immigrant Integration in Low-Income Urban Neighborhoods: Improving Economic Prospects and Strengthening Connections for Vulnerable Families [PDF]

open access: yes, 2007
Explores the financial welfare of immigrant groups in ten low-income urban communities, comparing key indicators of economic well-being, advancement, and integration across six immigrant and four U.S.-born race/ethnic ...
Karina Fortuny   +3 more
core  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Ethnic Diversity and Civil War [PDF]

open access: yes
We construct a model in which a number of equally powerful ethnic groups compete for power by engaging in civil war. In non-redistributive equilibrium, ethnically homogeneous and ethnically diverse countries face a lower probability of civil war than ...
Lagerlöf, Nils-Petter   +1 more
core  

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

Poverty and Inequality among Ethnic Groups in Chile [PDF]

open access: yes
Despite two decades of rapid growth, indigenous Chileans are disproportionately poor. However, income data obtained from non-representative surveys yield imprecise estimates of poverty and inequality. This paper therefore estimates poverty and inequality
Andrei Roman   +2 more
core  

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