Results 61 to 70 of about 15,081,734 (309)

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

QUANTITATIVE ASSESSMENT OF THYROID GLAND VOLUME AMONG THE ETHNIC GROUPS OF KARACHI POPULATION

Pakistan Journal of Medicine and Dentistry, 2019
Objectives: Thyroid gland volume varies from population to population. In this study mean thyroid gland volume among the ethnic groups in Karachi population was determined.
Mahrukh Kamran, Iffat Raza, Maria Mohiuddin, Nausheen Adnan, Sadaf Shaheen, Rabia Rehan   +5 more
doaj  

Effects of erythromycin on γ-glutamyl cysteine synthetase and interleukin-1β in hyperoxia-exposed lung tissue of premature newborn rats

Jornal de Pediatria, 2014
Objective: To explore the effect of erythromycin on hyperoxia-induced lung injury. Methods: One-day-old preterm offspring Sprague-Dawley (SD) rats were randomly divided into four groups: group 1, air + sodium chloride; group 2, air + erythromycin;group 3,
Cheng Cai, Gang Qiu, Xiaohui Gong, Yihuan Chen, Huanhu Zhao   +4 more
doaj   +1 more source

Ethnic discrimination in hiring: comparing groups across contexts. Results from a cross-national field experiment

Journal of Ethnic and Migration Studies, 2019
Existing field experimental research unequivocally shows the existence of ethnic discrimination in the labour market. Furthermore, studies have documented considerable variation in discrimination rates across countries.
Bram Lancee
semanticscholar   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Dynamics of Ethnocontact Zones in the Turkic Republics of the Ural-Volga Region in the Post-Soviet Period

Регионология
Introduction. The interest of world science in assessing the ethnic diversity of countries and regions predetermines the development of the concept of ethnocontact zones. To test new methods within the framework of the concept, there is a need to conduct
Andrei G. Manakov, Natalia K. Terenina, Ivan A. Ivanov   +2 more
doaj   +1 more source

Racial and Ethnic Disparities in COVID-19–Related Infections, Hospitalizations, and Deaths

Annals of Internal Medicine, 2020
Data suggest that impacts of COVID-19 differ among U.S. racial/ethnic groups. This systematic review evaluates racial/ethnic disparities in SARS-CoV-2 infection rates and COVID-19 outcomes, factors contributing to disparities, and interventions to reduce
K. Mackey, Chelsea K. Ayers, Karli K. Kondo, S. Saha, S. Advani, Sarah Young, H. Spencer, Max Rusek, Johanna Anderson, S. Veazie, Mia Smith, D. Kansagara   +11 more
semanticscholar   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

‘I do want to ask, but I can’t speak’: a qualitative study of ethnic minority women’s experiences of communicating with primary health care professionals in remote, rural Vietnam

International Journal for Equity in Health, 2017
Background Ethnic minority groups in Vietnam experience economic, social and health inequalities. There are significant disparities in health service utilisation, and cultural, interpersonal and communication barriers impact on quality of care.
Shannon McKinn, Thuy Linh Duong, Kirsty Foster, Kirsten McCaffery   +3 more
doaj   +1 more source

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

FEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López, Özge Yilmaz Ardicli, Mübeccel Akdis   +2 more
wiley   +1 more source