Results 61 to 70 of about 6,177,093 (289)
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
QUANTITATIVE ASSESSMENT OF THYROID GLAND VOLUME AMONG THE ETHNIC GROUPS OF KARACHI POPULATION
Objectives: Thyroid gland volume varies from population to population. In this study mean thyroid gland volume among the ethnic groups in Karachi population was determined.
Mahrukh Kamran +5 more
doaj
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Background Ethnic minority groups in Vietnam experience economic, social and health inequalities. There are significant disparities in health service utilisation, and cultural, interpersonal and communication barriers impact on quality of care.
Shannon McKinn +3 more
doaj +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Ethnic Studies Newsletter Vol. 8 No. 1
Six page newsletter from the Ethnic Studies department dated November 1989. Newsletter is Volume 8, Number 1. Newsletter includes Feature recognizing the following three faculty members who joined Ethnic Studies since the last newsletter: Dr.
Ethnic Studies Department;
core +1 more source
Introduction. The interest of world science in assessing the ethnic diversity of countries and regions predetermines the development of the concept of ethnocontact zones. To test new methods within the framework of the concept, there is a need to conduct
Andrei G. Manakov +2 more
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Introduction: In ABO system, O blood group is universal blood donor group. Knowing one's blood type is important for prevention of transfusion mis-match between recipients and donors.
Barun Mahat +8 more
doaj +1 more source
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source

