Results 61 to 70 of about 6,177,093 (289)

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

QUANTITATIVE ASSESSMENT OF THYROID GLAND VOLUME AMONG THE ETHNIC GROUPS OF KARACHI POPULATION

open access: yesPakistan Journal of Medicine and Dentistry, 2019
Objectives: Thyroid gland volume varies from population to population. In this study mean thyroid gland volume among the ethnic groups in Karachi population was determined.
Mahrukh Kamran   +5 more
doaj  

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

‘I do want to ask, but I can’t speak’: a qualitative study of ethnic minority women’s experiences of communicating with primary health care professionals in remote, rural Vietnam

open access: yesInternational Journal for Equity in Health, 2017
Background Ethnic minority groups in Vietnam experience economic, social and health inequalities. There are significant disparities in health service utilisation, and cultural, interpersonal and communication barriers impact on quality of care.
Shannon McKinn   +3 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Ethnic Studies Newsletter Vol. 8 No. 1

open access: yes, 1989
Six page newsletter from the Ethnic Studies department dated November 1989. Newsletter is Volume 8, Number 1. Newsletter includes Feature recognizing the following three faculty members who joined Ethnic Studies since the last newsletter: Dr.
Ethnic Studies Department;
core   +1 more source

Dynamics of Ethnocontact Zones in the Turkic Republics of the Ural-Volga Region in the Post-Soviet Period

open access: yesРегионология
Introduction. The interest of world science in assessing the ethnic diversity of countries and regions predetermines the development of the concept of ethnocontact zones. To test new methods within the framework of the concept, there is a need to conduct
Andrei G. Manakov   +2 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

O Blood Group among Medical Students in a Medical College of Nepal: A Descriptive Cross-sectional Study

open access: yesJournal of Nepal Medical Association, 2019
Introduction: In ABO system, O blood group is universal blood donor group. Knowing one's blood type is important for prevention of transfusion mis-match between recipients and donors.
Barun Mahat   +8 more
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

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