Results 171 to 180 of about 9,665,153 (294)

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

Buryat Ethnic Identity at Various Stages of Ethnic History

, 2020
Bair Nanzatov, Marina Sodnompilova
openaire   +1 more source

In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols

FEBS Open Bio, EarlyView.
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton, Fang Zhao, Reeta Davis, Meg Walsh, Kevin E O'Connor, David O'Connell, Tanja Narancic   +6 more
wiley   +1 more source

Performance of age-adjusted whole genome sequencing telomere length in idiopathic pulmonary fibrosis. [PDF]

Am J Respir Crit Care Med
Kim JS, Receveur B, Zhang D, Ma SF, Huang Y, McGroder C, Putman RK, Podolanczuk AJ, Rotter JI, Rich SS, Flaherty KR, Lee JS, Lasky JA, Raghu G, Murray S, Spino C, Martinez FJ, Oh A, Lynch DA, Humphries SM, Adegunsoye A, Oldham JM, Hunninghake GM, Garcia CK, Taub M, Mathias RA, Cho MH, Barr RG, Noth I, Mychaleckyj JC, Manichaikul A, Newton CA.   +31 more
europepmc   +1 more source

Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus

FEBS Open Bio, EarlyView.
BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima, Gustavo Narvaes Guimarães, Emilyane de Oliveira Santana Amaral, Bianca Caroline Figueiredo Bianco, Manuel Jara‐Espejo, Sérgio Roberto Peres Line, Ana Paula de Souza, Aline Cristiane Planello   +7 more
wiley   +1 more source

Prevalence, risk factors, and racial disparities in probable and possible dementia: the national health and aging trends study. [PDF]

J Prev Alzheimers Dis
Lee YS, Cruz JA, Kabakibi M, Moore A, Lee JA, Jun HJ.   +5 more
europepmc   +1 more source

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

FEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia, Rachel Heilmann, Maximiliano Barrientos, Laura MacNeill, Ingrid Vallee, Sarah K. Schultz, Patrick O'Donoghue, Angelica A. Moresco, Victoria M. Siu, Ilka U. Heinemann   +9 more
wiley   +1 more source

Environmental and ethnic differences in short-term risk of first acute myocardial infarction: a prospective multiethnic cohort protocol. [PDF]

Front Public Health
Wang B, Zhang Z, Lu W, Wang G, Chen K, Gu W, Shu Y, Wang J, Zhang T, Zhang Y, Wang R, Xu L, Xie P.   +12 more
europepmc   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

Ethnic Disparities in Clinical Decision-Making for Rapid Tranquillisation in Adult Forensic Mental Health Inpatient Settings: A Qualitative Study. [PDF]

Int J Ment Health Nurs
Pedersen ML, Baker J, Munk-Olsen T, Gildberg FA.   +3 more
europepmc   +1 more source