Results 121 to 130 of about 136,141 (296)
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
, 2008 textCulture integrates more than ideology and tradition. These cultural elements are supplementary factors that unite under certain conditions to assist in the development and understanding of what is right, wrong and/or expected within a group. Ideology
Parker, Amber Danielle
core
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Ethnic helping and group identity: A study among majority group children
, 2014 Two vignette studies were conducted on children's evaluations of ethnic helping. In the first study, 272 native Dutch children (mean age = 10.7) evaluated a child who refused to help in an intra-group context (Dutch-Dutch or Turkish-Turkish) or inter ...
Sierksma, Jellie; id_orcid +9 more
core +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Architectural styles and ethnic identity in medieval to modern Cyprus [PDF]
, 2005 Archaeologists and art historians have often attempted to identify ethnic groups by means of specific stylistic traits in their art and architecture. Close contextual examination, however, reveals that different groups in different contexts can use the ...
Given, M.
core
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Validation of the multigroup ethnic identity measure among ethnic Armenian adolescents in Lebanon
, 2008 The factor structure of the 12-item Armenian Multigroup Ethnic Identity Measure (MEIM) and its relation to self-esteem were examined among adolescents of Armenian descent (n = 525) in Lebanon.
Kazarian S.S., Boyadjian M.D.
core +1 more source
Tatar identity: current state and perspectives
Историческая этнология, 2016 Identity processes take place in different sociopolitical conditions and depend upon their contexts. Since the social crisis and the associated identity crisis, Russian society has been faced with the task of forming a new common country identity that ...
Rafael S. Khakimov
doaj
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source