Advanced Science, EarlyView.This study reveals that the Fgl2‐FcγRIIB signaling axis is a key mechanism by which MDSCs mediate tumor immune evasion. Tumor‐derived exosomes systemically activate MDSCs via this pathway, positioning this axis as a promising broad‐spectrum target for cancer immunotherapy.
Fenglin Lin +12 more
wiley +1 more source
Evaluation of cross-ethnic emotion recognition capabilities in multimodal large language models using the reading the mind in the eyes test. [PDF]
Sci RepRefoua E +5 more
europepmc +1 more source
Leveraging Artificial Intelligence and Large Language Models for Cancer Immunotherapy
Advanced Science, EarlyView.Cancer immunotherapy faces challenges in predicting treatment responses and understanding resistance mechanisms. Artificial intelligence (AI) and machine learning (ML) offer powerful solutions for cancer immunotherapy in patient stratification, biomarker discovery, treatment strategy optimization, and foundation model development.
Xinchao Wu +4 more
wiley +1 more source
Emotional belonging and cultural identity: a systematic review of collective emotions among indigenous and minority groups. [PDF]
Front SociolGuerra-Ayala MJ +4 more
europepmc +1 more source
Adult Sex Ratio as a Demographic Feedback Linking Mating Systems, Parental Care, and Evolution
Advanced Science, EarlyView.Breeding systems are some of the most diverse social behavior, and our team is investigation the evolutionary causes of this diversity. This review summarises our research carried out at the University of Bath. We argue that demographic components of wild populations, especially the adult sex ratio, plays a key role driving breeding system variation ...
Tamás Székely, Oscar G. Miranda
wiley +1 more source
Chinese Singaporean Children's Expectations About Peer Group Norms in the Context of Wealth and Ethnicity. [PDF]
Dev SciPaquette A +3 more
europepmc +1 more source
Advanced Science, EarlyView.CTBPro is a next‐generation cholera toxin B–based tracer engineered by fusing CTB to the ultra‐stable fluorescent protein mBaojin. Exhibiting markedly enhanced molar brightness, CTBPro enables high‐fidelity neuronal labeling across multiple administration routes.
Xinghua Quan +12 more
wiley +1 more source
Perceived cultural continuity, self-schemas, self-esteem, and psychological distress among members of ethnic groups with endangered scripts in Southwest China. [PDF]
Front PsycholZhang X, Li Z.
europepmc +1 more source
Advanced Science, EarlyView.Plastin‐2 (PLS2) is identified as a dual‐function receptor on DCs that mediates both nanoparticle uptake and immunomodulation. A nanobody‐LNP platform is engineered to integrate antigen delivery with relicensing DCs. The therapeutic strategy elicits potent anti‐tumor T cell responses and leads to significant inhibition of established tumors in vivo ...
Shugang Qin +9 more
wiley +1 more source
king Do socioeconomic inequalities contribute to the high prevalence of child developmental risk in an ethnically diverse, socioeconomically disadvantaged population? A Born in Bradford's Better Start (BiBBS) study. [PDF]
BMJ Paediatr OpenMooney KE +5 more
europepmc +1 more source