Results 191 to 200 of about 1,805,436 (316)

A Novel Function of Nonadecanoic Acid in Regulating Glucose Homeostasis

Advanced Science, EarlyView.
This study identifies the odd‐chain fatty acid C19:0 as an endogenous ligand of GPR120 that promotes glucose homeostasis via Gαq signaling. In obesity, elevated palmitic acid suppresses endogenous C19:0 production through a miRNA–PPARα–HACL1 pathway, offering a promising direction for understanding the role of OCFAs in human health.
Yanting Hou, Yinghua Ma, Qin Liu, Dingling Ma, Yuxin Tong, Lili Xu, Xiaolong Chu, Jingzhou Wang, Maodi Liang, Mengyuan Zhao, Huizi Zhang, Yurui Su, Jianxin Xie, Cuizhe Wang, Jun Zhang   +14 more
wiley   +1 more source

Understanding the Current Landscape of Health Disparities Research Among Youth With Juvenile Idiopathic Arthritis. [PDF]

J Rheumatol
Woo JMP, Hetrick R.
europepmc   +1 more source

Ethnic nomenclature [PDF]

British Journal of Psychiatry, 1991
openaire   +2 more sources

Farnesyltransferase Deficiency in Cardiomyocytes Initiates Senescence and Contributes to Cardiac Fibrosis

Advanced Science, EarlyView.
Lipid overload suppresses SREBF2‐mediated FNTB expression, leading to defective Lamin A maturation and nuclear envelope instability. This nuclear catastrophe triggers a pro‐fibrotic senescence program in cardiomyocytes. Notably, restoring nuclear integrity via AAV9‐based gene therapy effectively attenuates cardiac remodeling, identifying the ...
Yuxiao Chen, Lian Lou, Xuan Zhang, Lin Yan, Qi Zhang, Wen Shi, Jie Ding, Xu Lin, Rong Jiang, Shuo Liu, Thida Sok, Pengli Wang, Yun Mou, Jie Han, Shenjiang Hu, Xiaogang Guo, Jian Yang   +16 more
wiley   +1 more source

Evaluating the impact of discordant and missing demographic information on population health assessments using linked electronic health records and Census Bureau microdata. [PDF]

PLOS Digit Health
Ouyang D, Limburg A, Rehkopf DH, Goldin J, Phillips RL, Udalova V, Ho DE.   +6 more
europepmc   +1 more source

Ethnicity, N. 9 : Ethnic Diversity and Ethnic Studies

, 2013
"Ethnicity" – a peer-reviewed journal was established by the Institute of Philosophy and Sociology (University of Latvia). The journal publishes original works about ethnicity in different fields of knowledge – sociology, history, social linguistics, social psychology, law, political science.
openaire   +1 more source

Size‐Modulated Mesoderm‐Endoderm Divergence and Myocardial Cavitation in Micropatterned Cardioids

Advanced Science, EarlyView.
Micropatterned cardioids, CRISPR‐engineered reporter hiPSCs, deep‐tissue imaging, and single‐cell RNA sequencing are integrated to model mesoderm‐endoderm co‐development. Heart‐foregut crosstalk promotes single large cavitation inside cardioids, resembling early heart chamber formation. ABSTRACT The human heart, originating from the splanchnic mesoderm,
Plansky Hoang, David W. McKellar, Andrew Kowalczewski, Nhu Y. Mai, Meng Chai, Xiaojun L. Lian, Yi Zheng, Jeffrey Amack, Nathan Tucker, Iwijn De Vlaminck, Huaxiao Yang, Benjamin D. Cosgrove, Zhen Ma   +12 more
wiley   +1 more source

More coercion, less support: A latent class analysis of post-incident reviews for mental health inpatients exposed to coercive practice. [PDF]

PLOS Ment Health
Beames L, Chua KC, Simpson A, Onwumere J.   +3 more
europepmc   +1 more source

Ethnicity, N. 8 : Ethnic Diversity and Ethnic Studies

, 2013
"Ethnicity" – a peer-reviewed journal was established by the Institute of Philosophy and Sociology (University of Latvia). The journal publishes original works about ethnicity in different fields of knowledge – sociology, history, social linguistics, social psychology, law, political science.
openaire   +1 more source

Mapping Genetic Regulation of Transcription to Identify Functional Variants and Genes Associated with Pancreatic Cancer Risk

Advanced Science, EarlyView.
Integration of a pancreatic eQTL map with a GWAS meta‐analysis identifies 82 putative functional variants and 15 genes. The association between rs11102484 and pancreatic cancer risk is observed in a total of 5699 cases and 8467 controls. The G allele of rs11102484 weakens ZNF263 binding and the silencer‐promoter interaction, thereby increasing ST7L ...
Xiaoyang Wang, Hui Geng, Zhengyan Yao, Yuan Jiang, Can Chen, Zequn Lu, Shuangshuang Tian, Ming Zhang, Ruiyan Liu, Chenxi Feng, Bin Li, Xiaoping Miao, Jianbo Tian, Shaokai Zhang, Ying Zhu   +14 more
wiley   +1 more source