Results 221 to 230 of about 995,471 (308)

Noninvasive Detection and Subtyping of Esophageal Cancer by Circulating Cell‐Free mtDNA Fragmentomics: A Multi‐Center Validation Study

Advanced Science, EarlyView.
Circulating cell‐free mitochondrial DNA provides a robust, noninvasive platform for early detection and histological subtyping of esophageal cancer. This large multi‐center study validates consistently high accuracy across ethnically and geographically diverse cohorts, demonstrating strong potential to transform clinical management. ABSTRACT Esophageal
Yue Liu, Wenying Yang, Yu Li, Siyuan Wang, Xiang Li, Fan Peng, Miao Dang, Huanqin Zhang, Huanmin Jiao, Yuqing Yang, Zhaoquan Su, Xiumin Ma, Zhiyun Gong, Renquan Lu, Jinliang Xing, Yang Liu   +15 more
wiley   +1 more source

An Explainable Multimodal Deep‐Learning Model Using Histopathological Image and Clinical Information for Prognosis Prediction in Colorectal Cancer: A Multi‐Center Cohort Study

Advanced Science, EarlyView.
This study develops a multimodal deep‐learning model that integrates clinical variables and histopathological images to predict survival outcomes in colorectal cancer. The multimodal model effectively stratifies patients into low‐ and high‐risk groups, demonstrating superior accuracy and generalizability across multiple independent cohorts.
Zhihan Jiang, Xiangchao Shi, Chenghan Su, Yao Ma, Rui Li, Menglei Chen, Jianxin Cui, Nicholas Hawkins, Robyn Ward, Xiangzhi Bai, Jitendra Jonnagaddala, Wei Fu, Xin Zhou   +12 more
wiley   +1 more source

Race, ethnicity, and language are underreported in hip fracture CPGs. [PDF]

Arch Orthop Trauma Surg
Mulakaluri A, Snyder EM, Young B, Kamal RN, Shapiro LM.   +4 more
europepmc   +1 more source

Deep Learning for AD Risk Screening and Progression Prediction

Advanced Science, EarlyView.
A pretrained MRI‐based deep learning model generalizes from Western cohorts to an independent Chinese cohort, detects Alzheimer's disease with high sensitivity, and identifies elevated AD risk years before diagnosis. Its risk scores align with cognition and plasma biomarkers, and individualized brain risk maps uncover clinically distinct subtypes ...
Bin Lu, Yan‐Rong Chen, Rui‐Xian Li, Ming‐Kai Zhang, Shao‐Zhen Yan, Guan‐Qun Chen, Jing‐Hua Wang, Wen‐Hui Chai, Francisco Xavier Castellanos, Paul M. Thompson, Jie Lu, Ying Han, Chao‐Gan Yan   +12 more
wiley   +1 more source

Unequal spending, unequal care: Race and ethnicity and their interactions with clinical and socioeconomic factors in health care expenditures among older adults with cardiovascular disease. [PDF]

J Manag Care Spec Pharm
Zakeri M, Arefin P, Sansgiry SS.
europepmc   +1 more source

Epigenetic Activation of ANGPTL4 Drives EBV‐Negative Gastric Cancer via Neutrophil Recruitment and NET Release via Stabilizing ANXA5

Advanced Science, EarlyView.
ANGPTL4 exhibits distinct promoter methylation patterns and expression profiles in EBV‐positive versus EBV‐negative gastric cancer. Secreted C‐terminal ANGPTL4 (cANGPTL4) acts as the dominant functional isoform driving GC proliferation, EMT, and neutrophil infiltration. cANGPTL4 promotes neutrophil recruitment via NF‐κB/CXCL8 axis.
Dandan Li, Xinqi Li, Xiangyin Luo, Jiayi Wang, Yiwei Zha, Zeng Zhou, Yanyan Chen, Qi Wang, Lingyun Xia, Weidong Leng, Shanshan Qin   +10 more
wiley   +1 more source

Racial and ethnic survival disparities in primary liver cancer in the United States: a National Cancer Database propensity score-matched study. [PDF]

Hepat Oncol
Ozer M, Goksu SY, Jones AL, Brown TJ, Sanford N, Verma N, Al Mutar S, Hsieh D, Kazmi SM.   +8 more
europepmc   +1 more source

Extreme Weather Events and Consumer Food Responses

Applied Economic Perspectives and Policy, EarlyView.
ABSTRACT This study investigates consumer food responses to Hurricanes Helene and Milton, which affected a swath of the Southeastern U.S. in 2024. Using representative consumer survey data from six affected states, we analyze 10 distinct food responses classified into ex ante and ex post responses, and examine their associations with food insufficiency
Ahmad Zia Wahdat, Joseph Balagtas
wiley   +1 more source

Do Universal Free School Meals Improve the Dietary Quality of Food‐At‐Home Purchases?

Applied Economic Perspectives and Policy, EarlyView.
ABSTRACT Since 2014, the number of schools offering universal free meals to all enrolled children without requiring annual meal applications has increased meaningfully. Using USDA's Purchase to Plate Crosswalk, a difference‐in‐differences framework, and a nationwide consumer panel, the effect of universal‐free‐meal exposure on the diet quality of food ...
Xueying Ma, Andres Cuadros‐Meñaca, Michael R. Thomsen   +2 more
wiley   +1 more source