Results 151 to 160 of about 1,315,571 (315)

Kv3.1 activation suppresses provoked and spontaneous seizures in a mouse Dravet syndrome model

Epilepsia, EarlyView.
Abstract Objective γ‐Aminobutyric acidergic (GABAergic) parvalbumin‐positive (PV+) interneurons are critical for maintaining cortical inhibitory tone, with their dysfunction predictably leading to epilepsy. Rapid PV+ interneuron firing is essential for their normal function and is maintained in part by potassium voltage‐gated channels.
Sheryl Anne D. Vermudez, Mustafa Q. Hameed, Yongho Choe, Gabrielle E. McGinty, Amanda M. Liebhardt, Rui Lin, Benjamin Hui, Yini Liang, David J. Arce, Henry H. C. Lee, Mustafa Sahin, Alexander Rotenberg   +11 more
wiley   +1 more source

Donkwa Enriched With Goron‐Tula (Azanza garckeana) Modulates Sexual Behavior and Activity of Enzymes Linked With Erectile Dysfunction in High‐Fat Diets/ Streptozotocin‐Induced (STZ/HFD) Diabetic Rats

Food Chemistry International, EarlyView.
(A) Mount number, (B) mount latency, (C) intromission number, and (D) intromission latency are the parameters of sexual behavior. Met = metformin. D100 = 100 Donkwa. D90G10 = 90% Donkwa + 10% Goron‐Tula. D85G15 = 85% Donkwa + 15% Goron‐Tula. D80G20 = 80% Donkwa + 20% Goron‐Tula. The mean ± standard error of the mean (SEM) expressed the results. *Values
O. T. Mamukuyomi, O. S. Ijarotimi, A. A. Badejo   +2 more
wiley   +1 more source

Nutrition and Metabolic Diseases: A Systematic Review of Functional Foods, Medicinal Plants, Phytochemicals, Bioactive Compounds and Nutrients Effective Against Metabolic Diseases

Food Chemistry International, EarlyView.
The study demonstrates how functional foods, medicinal plants, phytochemicals, bioactive compounds and essential nutrients combat metabolic diseases. It highlights their mechanisms, including antioxidant, anti‐inflammatory, insulin‐sensitising, lipid‐regulating, gut microbiota‐modulating and mitochondrial‐enhancing effects, leading to improved ...
Chinaza Godswill Awuchi, Sana Noreen, Sonia Morya   +2 more
wiley   +1 more source

Annona squamosa: Phytochemical Fingerprinting, Health‐Improving Traits, and Functional Applications

Food Chemistry International, EarlyView.
Annona squamosa (custard apple) is a nutrient‐rich fruit containing diverse bioactive phytochemicals (e.g., acetogenins, flavonoids, and alkaloids) that contribute to multiple health benefits, including antioxidant, antihyperlipidemic, and antimicrobial activities, highlighting its potential as a functional food and medicinal resource.
Mohamed Fawzy Ramadan, Jumanah Reda Kurdi, Manar Yahya Alzahrani, Asmaa Ibrahim Alshaikhi, Jumanah Samir Hazzazi   +4 more
wiley   +1 more source

Pharmacokinetics of Ethyl Glucuronide and Ethyl Sulfate and Pharmacodynamic Effects Following Intravenous and Oral Administration of Ethanol to Exercised Horses. [PDF]

Drug Test Anal
Knych HK, Blea J, Scollay M, Kass PH, McKemie DS.   +4 more
europepmc   +1 more source

A modular and programmable electrolyte platform: Covalently anchored thermochromic hydrogels for on‐demand electrochromic devices

FlexMat, EarlyView.
Developing stable, multifunctional hydrogel electrolytes without compromising performance presents a considerable challenge in the field. In this study, we introduce a material design strategy with broad applicability to combinations of functional polymeric segments, ionic monomers, and salts.
Manyu Liu, Jixiang Cui, Yulu Cai, Bin Deng, Yiqian Zhao, Chaohong Zhang, Shiguo Zhang, Hong Meng   +7 more
wiley   +1 more source

Quantification of ethyl glucuronide, ethyl sulfate, nicotine, and its metabolites in human fetal liver and placenta

Forensic Toxicology, 2017
Madeleine J. Swortwood, S. Bartock, K. Scheidweiler, S. Shaw, P. Filis, A. Douglas, Peter J. O'Shaughnessy, U. Soffientini, B. Lucendo-Villarin, J. Iredale, David C. Hay, Paul A. Fowler, M. Huestis   +12 more
semanticscholar   +1 more source

Interactions between lactobacillus and yeast: A recent update

Food Biomacromolecules, EarlyView.
Abstract Lactobacillus and yeast are microorganisms widely distributed in nature. Their interactions significantly impact fermentation processes, human health, and medical care. However, there is a lack of a systematic summary of the characteristics of these interactions, and the mechanisms underlying these interactions remain unclear.
Yang Chen, Mengyuan Liu, Mengchen Li, Zhiyun Yue, Yang Mu, Chao Wang, Lusha Xia, Junjun Gao, Mingye Peng, Ran Wang, Mengzhou Zhou   +10 more
wiley   +1 more source

Optimized Copper Pretreatment Protocols for Premium Green Raisin Production via Vacuum Impregnation and Metallo‐Complex Stabilization

Future Postharvest and Food, EarlyView.
ABSTRACT Green raisin production is limited by rapid chlorophyll degradation during drying. This study evaluated copper metallo‐complex formation to stabilize green pigmentation in Vitis vinifera cv. Thompson Seedless grapes. Pretreatments with copper sulfate (CuSO4) pentahydrate (2%–6% w/v) were applied via dipping and vacuum impregnation (2–10 min ...
Sakharam Kale, Prerna Nath, Pankaj Kannaujia   +2 more
wiley   +1 more source

Anti‐Inflammatory Effects of Punicic Acid and Its Molecular Mechanisms in RAW264.7 Cells and Zebrafish

Food Safety and Health, EarlyView.
Punicic acid (PA) was enriched and purified from PSO by molecular distillation with significant anti‐inflammatory activity to RAW264.7 cells, as well as to zebrafish. Anti‐inflammatory mechanism involved regulating NF‐κB and MAPK signaling pathways. ABSTRACT Punicic acid (PA) is the main fatty acid in pomegranate seeds, which shows multiple biological ...
Mengqi Zhang, Caiyun Feng, Mengyao Zhu, Xu Guo, Yingying Chen, Wenwen Hu, Fei Dong, Jinyue Sun, Chao Liu   +8 more
wiley   +1 more source