Results 181 to 190 of about 1,315,571 (315)

A rationally designed peptide targeting trypsin‐like enzymes impairs feeding and redox homeostasis in Anticarsia gemmatalis (Lepidoptera: Erebidae)

open access: yesPest Management Science, EarlyView.
GORE3 interacts with digestive proteases in Anticarsia gemmatalis, promoting digestive inhibition, oxidative stress, and midgut cell damage. These physiological disturbances diminish larval survival and feeding damage on soybean plants, emphasizing the potential of GORE3 as a bioinsecticidal peptide for pest control.
Daniel Guimarães Silva Paulo   +14 more
wiley   +1 more source

Breaking Alzheimer's Disease Barrier: The Role of Xanthoceras sorbifolia Bunge Oil in Gut‐Brain Axis and TLR4/Myd88/MAPK Pathway Inhibition

open access: yesPhytotherapy Research, EarlyView.
ABSTRACT Alzheimer's disease (AD) is a progressive neurodegenerative disorder associated with cognitive decline and neuroinflammation. Xanthoceras sorbifolia Bunge oil (XSBO), a woody plant oil rich in bioactive fatty acids, has shown potential health benefits.
Lijing Du   +8 more
wiley   +1 more source

Catechins and Their Effect on the Gut Microbiome in Health and Cancer

open access: yesPhytotherapy Research, EarlyView.
ABSTRACT Catechins are a group of flavonoids found primarily in green tea, fruits, and berries; they play a significant role in the modulation of the gut microbiota, thereby having an impact on gut health and cancer prevention. Owing to their low bioavailability, catechins are transformed by the gut microbiota into various bioactive metabolites such as
Prakash Monika   +5 more
wiley   +1 more source

Notoginsenoside R2 Antagonizes Renal Interstitial Fibrosis by Regulating Fatty Acid Oxidation via the CASP2/ALDH3A1 Axis

open access: yesPhytotherapy Research, EarlyView.
Proposed mechanism by which notoginsenoside R2 (NGR2) attenuates renal interstitial fibrosis. In injured renal tubular epithelial cells, CASP2 downregulation and enhanced ubiquitin‐dependent degradation of ALDH3A1 disrupt mitochondria‐associated endoplasmic reticulum membranes (MAMs) and impair fatty acid oxidation (FAO), leading to lipid accumulation ...
Guanting Chen   +10 more
wiley   +1 more source

Moisture Change Model for Active Package of Dry Dosage Forms Under Consumer Use Condition

open access: yesPackaging Technology and Science, EarlyView.
A simple mathematical model was developed to estimate moisture contents of dry dosage product packaged with desiccant during in‐use condition, where each dosage is taken out periodically. The model utilizes sequential summation of individual steps of package layer's moisture transmission and internal equilibration among the headspace, product and ...
Duck Soon An, Dong Sun Lee
wiley   +1 more source

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