Results 111 to 120 of about 2,614,577 (295)

Smear layer removal efficacy of different irrigating solutions: A comparative scanning electron microscope evaluation

open access: yesIndian Journal of Dental Research, 2014
Aims: Comparative evaluation of cleaning efficacy of smear layer removal by different irrigating solutions such as 2.5% sodium hypochlorite (NaOCl), 17% ethylenediaminetetraacetic acid (EDTA) with 2.5% NaOCl, 10% citric acid with 2.5% NaOCl and 1 ...
B Ahir   +3 more
doaj   +1 more source

In Situ Profiling of Nanoscale Strains Uncovers Mechano‐Architectural Predictors of Aging and Osteoarthritis Emergence

open access: yesAdvanced Science, EarlyView.
In situ mechanical loading of osteoarthritis‐prone murine knee joints reveals that spatial alterations in subchondral plate microarchitecture precede cartilage loss and promote a shift from coordinated epiphyseal strain dissipation in healthy joints to focal subchondral strain concentration in osteoarthritis‐prone joints.
Aikta Sharma   +10 more
wiley   +1 more source

Bimetallic Clusters of Pyridine-Appended Ethylenediaminetetraacetic Acid (EDTA)-amides in Designing 1D and 2D Coordination Frameworks

open access: yes, 2016
A new ligand containing an ethylenediaminetetraacetic acid (EDTA) core and four amidopyridines was synthesized for the first time and was shown capable of forming bimetallic species (MnII/ZnII/CoII), which were further assembled into one- and two ...
Lalit Rajput (1744114)   +1 more
core   +1 more source

O‐GlcNAcylation Regulation of SNAP29‐Dependent Autophagy Activation Dictates Chemoresistance in Gastric Cancer

open access: yesAdvanced Science, EarlyView.
Model illustrating the proposed mechanism by which chemotherapy‐induced downregulation of OGT disrupts SNAP29 O‐GlcNAcylation, promoting STX17‐SNAP29‐VAMP8 SNARE complex assembly and protective autophagy, leading to chemoresistance, which in turn establishes a feedforward loop to perpetuate drug tolerance.
Liang Tang   +9 more
wiley   +1 more source

Synthesis and Preliminary Characterization of a New Hexadentate Sequestrant in the Ethylenediaminetetrapropionic Acid Class

open access: yesScientific Papers Animal Science and Biotechnologies, 2023
Ethylenediaminetetraacetic acid (EDTA) (E-385) as such and/or derivatized (salified) occupies a separate chapter, of wide interest in food sciences, because of its coordinating (sequestering) competences towards various organic and/or inorganic ...
Mihaela Cazacu   +5 more
doaj  

A Blood‐Derived Factor Rescues ALS: Platelet Factor 4 Activates OPTN‐Dependent Autophagy to Clear SOD1 Aggregates Independently of PINK1

open access: yesAdvanced Science, EarlyView.
Systemic platelet factor 4 (PF4) is significantly depleted in amyotrophic lateral sclerosis (ALS). Peripheral PF4 replenishment restores central proteostasis by driving OPTN‐dependent, PINK1‐independent selective autophagy in motor neurons. This intervention effectively clears toxic SOD1 aggregates, blunts glial activation, and preserves neuromuscular ...
Qingjian Xie   +12 more
wiley   +1 more source

YAP1‐Driven Pathogenic Fibro‐Adipogenic Progenitors Secrete IL‐6 and FGF21 to Mediate Muscle‐Bone Crosstalk and Promote Bone Loss

open access: yesAdvanced Science, EarlyView.
Fibro‐adipogenic progenitors (FAPs) in atrophic muscle undergo YAP1‐driven pathogenic activation, secreting IL‐6 and FGF21 as bone‐catabolic myokines that mediate muscle‐bone crosstalk and promote bone loss. Genetic or pharmacological targeting of this YAP1‐FAP‐myokine axis rescues skeletal deterioration, identifying FAP‐derived myokines as therapeutic
Xiaoyu Cai   +16 more
wiley   +1 more source

Postoperative pain after endodontic treatment with glycolic acid as final irrigant using reciprocating and rotary instrumentation in a noninferiority trial

open access: yesScientific Reports
This randomized clinical trial was designed to evaluate whether glycolic acid (GA) is non-inferior to ethylenediaminetetraacetic acid (EDTA) regarding postoperative pain after endodontic treatment.
Paola Serraglio Figueiredo   +11 more
doaj   +1 more source

Polarographic determination of uranyl adsorption onto poly(acrylamide-g-ethylenediaminetetraacetic acid) hydrogels in the presence of cadmium and lead

open access: yes, 2003
Poly(acrylamide-g-ethylenediaminetetraacetic acid) [P(AAm-g-EDTA)] hydrogels with various compositions were prepared from ternary mixtures of acrylamide, ethylenediaminetetraacetic acid and water by using Co-60 gamma-rays.
Caykara, T, Kantoglu, O, Inam, RECAİ
core   +1 more source

The Natural Product Corramycin Acts as a DNA Gyrase Poison and Overcomes Fluoroquinolone Resistance in Mycobacterium tuberculosis

open access: yesAdvanced Science, EarlyView.
Corramycin, a myxobacterial natural product antibiotic, exhibits potent bactericidal activity against multidrug‐resistant Mycobacterium tuberculosis. The compound hijacks bacterial transporters such as BacA and OppABCD to enter the cell and inhibits DNA synthesis through a previously unrecognized mode of DNA gyrase poisoning, locking the enzyme in an ...
Franziska Fries   +25 more
wiley   +1 more source

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