Results 141 to 150 of about 171,695 (305)

Effect of different chelating agents, with and without activation, including XP-endo Finisher, on root dentin microhardness: An in vitro study

open access: yesSaudi Endodontic Journal
Introduction: Irrigating solutions used during root canal preparation may affect the physical properties of dentin. Therefore, careful selection of irrigants is required which have maximum benefits with minimum undesirable properties.
Mahmoud Mohamed A. Sherif   +2 more
doaj   +1 more source

Molecular mechanism of ischemic postconditioning in promoting diabetic ischemic brain injury repair via the microRNA‐34a–BDNF–SIX3 signaling axis

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Diabetes combined with ischemic stroke (DMIS) exacerbates brain infarct size and neuronal damage compared to nondiabetic ischemic stroke (IS). This study reveals that microRNA‐34a (miR‐34a) plays a key role in DMIS pathogenesis: miR‐34a directly targets and suppresses brain‐derived neurotrophic factor (BDNF) and Sine oculis homeobox 3 (SIX3), promoting
Ling Zhao   +5 more
wiley   +1 more source

USB1 deficiency disrupts neutrophil maturation via RNA dysregulation independent of global pre‐mRNA splicing

open access: yesAnimal Models and Experimental Medicine, EarlyView.
This graphical abstract illustrates the essential role of USB1 in neutrophil maturation. In normal myeloid cells, USB1 acts as an RNA exonuclease, trimming RNA tails to maintain proper RNA network function, which supports the differentiation of myeloid progenitor cells into mature neutrophils.
Hang Li   +6 more
wiley   +1 more source

Human Leukocyte Elastase Triggered Nanoparticles for Targeted Antimicrobial Delivery and Oral Microbial Modulation

open access: yesAdvanced NanoBiomed Research, EarlyView.
This study explores enzyme‐responsive nanoparticles for targeted antimicrobial release in inflamed oral environments. Nanoparticles formed by complexing peptides and chlorhexidine respond to human leukocyte elastase and release chlorhexidine selectively. P7 (ECAAPVCE)‐based formulations show optimal properties and stability, with antimicrobial activity
Mohammed A. Hadis   +9 more
wiley   +1 more source

Comparison of Receptor‐Mediated Endocytosis and Its Application to Enhance DNA Transfection by TFAMoplex

open access: yesAdvanced NanoBiomed Research, EarlyView.
We developed an assay to distinguish cellular binding from internalization. Compatible with microscopy and high‐throughput screening, the method identifies ligand‐mediated uptake. Applying top candidates to a protein‐based DNA carrier enhanced transfection efficiency, providing a rational strategy to improve non‐viral gene delivery systems.
David Scherer   +5 more
wiley   +1 more source

Improved Dry‐Pressing Strategy for Fabricating Double‐Sided Rough YSZ Electrolyte Thin Films and Their Performance in Solid Oxide Cells

open access: yesAsia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT This study addresses limitations of the conventional dry‐pressing method for electrolyte‐supported films—smooth surfaces, excessive thickness, and fragile supports inducing damage. We propose an innovative camphor–quartz sand composite architecture to construct a five‐layer (camphor/quartz sand/YSZ/quartz sand/camphor) system, enabling thin ...
Hong Chang   +8 more
wiley   +1 more source

Green Fuel Combustion Synthesis of CeO2 and Ag/CeO2 Nanoparticles for Photocatalytic and Antibacterial Applications

open access: yesAsia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT Silver‐doped cerium oxide nanoparticles (Ag/CeO2 NPs) were synthesized using Ricinus communis seed extract as a bio‐derived fuel in a solution combustion method. The combustion reaction, carried out at 450°C with AgNO3 and (NH4)2[Ce (NO3)6] as metal precursors, produced CeO2 and Ag/CeO2 NPs.
T. N. Ravishankar   +5 more
wiley   +1 more source

A Novel Green Method for Producing Medical‐Grade Chitosan From Loligo plei Squid Pens

open access: yesJournal of Applied Polymer Science, EarlyView.
This work demonstrates a sustainable and simplified process for the production of medical‐grade chitosan from the feathers of the squid Loligo plei, employing mild chemical treatments to preserve the integrity of the polymer while achieving high purity and performance.
Talita Martins   +7 more
wiley   +1 more source

A cost‐effective DNA extraction protocol for long‐read sequencing in non‐model plants

open access: yesApplications in Plant Sciences, EarlyView.
Abstract Premise Third‐generation sequencing has revolutionized genomics, enabling in‐depth analysis of genome sequence, structure, and epigenetic features. Yet, extracting high‐quality DNA for long‐read sequencing remains a bottleneck—particularly in non‐model plants, such as mature trees growing in natural environments, which often contain abundant ...
Sofia Gaischuk   +6 more
wiley   +1 more source

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