Case Report: When access is limited: using CYP3A4 inhibition to maintain clinical benefit from elexacaftor/tezacaftor/ivacaftor. [PDF]
Hiscock K +4 more
europepmc +1 more source
NbRD21 protease controls receptor kinase homeostasis in Nicotiana benthamiana
Proteomic analysis revealed that receptor kinases (red) accumulate higher in rd21 knockout Nicotiana benthamiana plants. Summary RD21‐like proteases are papain‐like cysteine proteases with a C‐terminal granulin domain that are abundant and ubiquitous in angiosperms and have often been implicated in immunity.
Alice Godson +13 more
wiley +1 more source
Comparison of the Blockbuster<sup>TM</sup> and Air-Q<sup>®</sup> Supraglottic Airway Devices as a Conduit to Blind Endotracheal Intubation in Paediatric Patients: A Randomised Control Trial. [PDF]
Pattanayak A +6 more
europepmc +1 more source
PlantRG: A Comprehensive and User‐Friendly Database for Plant Resistance Gene Analogs (RGAs)
ABSTRACT Resistance genes are critical for plant defence against biotic stresses, and building a comprehensive, integrated data resource platform for these genes holds great significance for plant research and agriculture. Here, we developed PlantRG (http://plantrg.bio2db.com), a user‐friendly plant resistance gene database, which is built on 2 163 397
Jinghua He +9 more
wiley +1 more source
Resolution of recurrent pancreatitis and nutritional recovery with CFTR modulator therapy in CFTR-related disorder: a case report. [PDF]
Jose FA.
europepmc +1 more source
MYB Factors: Hubs of Plant Stress and Hormone Crosstalk
ABSTRACT MYB transcription factors function as main regulatory hubs that integrate environmental signals with multi‐hormonal pathways to synchronize plant growth, metabolism and stress responses. This review delineates the regulatory roles of MYB in the signalling pathway of salicylic acid, jasmonic acid, ethylene and abscisic acid signalling.
Aye Aye Htun +9 more
wiley +1 more source
Design, synthesis, drug-likeness, and molecular dynamics evaluations of monobrominated amathamide G analogs as potential ligands for D2-like dopamine receptors. [PDF]
Navarrete-Gutiérrez A +5 more
europepmc +1 more source
Caregiver Mental Health and Its Relation to Child and Adolescent Mental and Behavioral Health in the Era of Highly Effective Modulator Therapy for Cystic Fibrosis. [PDF]
Duncan CL +14 more
europepmc +1 more source
ABSTRACT Tandem kinases are emerging regulators of plant immunity, but the downstream defense programs they activate remain poorly understood. Stripe rust, caused by Puccinia striiformis f. sp. tritici (Pst), is a major constraint on global wheat production. The Yr15 resistance gene, derived from wild emmer wheat, encodes the tandem kinase protein WTK1.
Liubov Govta +5 more
wiley +1 more source
Polymicrobial Extracellular Vesicles Reduce the Innate Immune Response of Human Cystic Fibrosis Bronchial Epithelial Cells. [PDF]
Charpentier LA +10 more
europepmc +1 more source

