Results 61 to 70 of about 34,094 (201)

The combination elexacaftor/tezacaftor/ivacaftor (ETI) modulates the de novo synthethic pathway of ceramides in a genotype-independent manner

open access: yes, 2023
We report here how the triple combination of drugs elexacaftor/tezacaftor/ivacaftor (ETI) alters the balance of the de-novo synthethic pathway of sphingolipids in primary cells of human bronchial epithelium.
Franceschi, Pietro   +17 more
core   +1 more source

Elevating sugar beet by-products into healthier, natural, and functional ingredients [PDF]

open access: yesExploration of Foods and Foodomics
Aim: This research was conducted on the hypothesis that refined sugars negatively affect health, require high energy for production, generate significant carbon emissions, and produce environmental waste.
Ahmet Görgülü
doaj   +1 more source

Longitudinal microbial and molecular dynamics in the cystic fibrosis lung after Elexacaftor–Tezacaftor–Ivacaftor therapy

open access: yesRespiratory Research, 2023
Background Cystic fibrosis (CF) is a genetic disorder causing poor mucociliary clearance in the airways and subsequent respiratory infection. The recently approved triple therapy Elexacaftor–Tezacaftor–Ivacaftor (ETI) has significantly improved lung ...
Christian Martin   +12 more
doaj   +1 more source

Impact of cystic fibrosis transmembrane conductance regulator modulator therapies on liver stiffness and liver enzymes: An observational perspective single‐center cohort study

open access: yesJPGN Reports, EarlyView.
Abstract Objectives The efficacy of cystic fibrosis transmembrane conductance regulator (CFTR)‐modulator therapies in preventing or ameliorating cystic fibrosis liver disease (CFLD) by correcting CFTR in cholangiocytes is not well‐documented. This study aimed to assess liver function during CFTR‐modulators.
Laura Giugliano   +12 more
wiley   +1 more source

Comparative Concept Study of Passive Hybrid Energy Storage Systems in 48 V Mild Hybrid Vehicles Varying Lithium-Ion Battery and Supercapacitor Technologies

open access: yesWorld Electric Vehicle Journal, 2019
A single energy storage technology will deliver either high power or high energy density. In high cycle applications like 48 V mild hybrid electric vehicles, lithium-ion batteries or supercapacitors have to be oversized to meet power, energy and cycle ...
Thorsten Grün, Martin Doppelbauer
doaj   +1 more source

The epigenetic landscape of plant defense: Unlocking nature's toolkit for new plant protection

open access: yesNew Plant Protection, EarlyView.
This review examines how epigenetic mechanisms regulate plant immune gene activation, repression, and priming, then links these natural regulatory layers to emerging epigenetic editing, discussing their potential for precise, heritable crop protection and the challenges.
Xuexia Liu, Zhenhui Zhong
wiley   +1 more source

L-3 Communications ETI Electric Propulsion Overview

open access: yes, 2020
L-3 Communications Electron Technologies Inc. (ETI) is a new company (formerly ETI is also producing 30cm xenon ion thrusters and power processor units (PPU) for the Jet Propulsion Laboratory's Dawn spacecraft and developing the power processor unit
Michael K De Pano   +5 more
core  

A Randomized Comparison of In-hospital Rescuer Positions for Endotracheal Intubation in a Difficult Airway

open access: yesWestern Journal of Emergency Medicine, 2018
Introduction: Emergency endotracheal intubation (ETI) is a common and critical procedure performed in both prehospital and in-hospital settings. Studies of prehospital providers have demonstrated that rescuer position influences ETI outcomes.
Joanna M. Le Parc   +7 more
doaj   +1 more source

Same Practices, Different Outcomes: Gender Gaps in Organic Certification

open access: yesSustainable Development, EarlyView.
ABSTRACT This paper examines gender differences in organic certification among Hungarian wineries and asks whether they reflect observable differences in sustainability engagement, organizational capabilities, and structural characteristics, or differences in how similar profiles translate into certified status.
Imre Fertő, Valéria Lekics
wiley   +1 more source

Mapping the Implementation Practices of the 15-Minute City

open access: yesSmart Cities
This paper delves into the rapidly progressing 15-Minute City concept, an innovative urban planning model that envisions a city where residents can access essential services and amenities within a 15-min walk or bike ride from their homes. Endorsed by UN-
Zaheer Allam   +4 more
doaj   +1 more source

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