Results 81 to 90 of about 3,485 (208)

Treatment of established osteoporosis: a systematic review and cost–utility analysis [PDF]

, 2002
Background and aims Osteoporosis is a systemic skeletal disease, characterised by low bone mass and microarchitectural deterioration of bone tissue with a subsequent increase in bone fragility and susceptibility to fracture.
J. E. Brazier, Stevenson, M., N.W. Calvert, J.A. Kanis, Kanis, JA, Stevenson, M, Calvert, N.W., Calvert, NW, M. Lloyd Jones, Brazier, JE, Lloyd Jones, M, Kanis, J.A., M. Stevenson, Brazier, J.E., Lloyd Jones, M., Calvert, N.   +15 more
core   +1 more source

Cost-Effectiveness of Pharmacological Treatments for Osteoporosis Consistent with the Revised Economic Evaluation Guidelines for Canada

MDM Policy & Practice, 2019
Introduction. Given the lack of independent analyses comparing numerous pharmacotherapies for osteoporosis, the study objective was to identify the optimal osteoporosis treatment based on a woman’s age, fracture history, and ability to tolerate oral ...
Doug Coyle
doaj   +1 more source

The prevention of corticosteroid-induced bone loss with intermittent cyclical etidronate.

, 1999
A prospective, randomised, double-blind, placebo controlled primary prevention trial was undertaken in 28 patients commencing low to moderate doses of corticosteroids for the first time.
Jenkins, EA, Wood, A, Cooper, Cyrus, Cooper, C, McCrae, FC, Walker-Bone, KE, Cawley, MI   +6 more
core   +1 more source

Isolated and combined use of bisphosphonates, statins and flavonoids in osteoporotic female rat

Brazilian Journal of Veterinary Medicine, 2014
. Amaral G.G., Del Carlo R.J., Oliveira T.T., Louzada M.J.Q., Valadares R.F.D., Ribeiro M.D. & Pinto A.S. [Isolated and combined use of bisphosphonates, statins and flavonoids in osteoporotic female rat.] Uso isolado e combinado de bisfosfonatos ...
Gláucia Guimarães Amaral, Ricardo Junqueira Del Carlo, Tânia Toledo de Oliveira, Mário Jefferson Quirino Louzada, Rilene Ferreira Diniz Valadares, Mariella Dias Ribeiro, Aloísio da Silva Pinto   +6 more
doaj  

Effect of medications on prevention of secondary osteoporotic vertebral compression fracture, non-vertebral fracture, and discontinuation due to adverse events: a meta-analysis of randomized controlled trials

BMC Musculoskeletal Disorders, 2019
Background Bone loss with aging and menopause increases the risk of fragile vertebral fracture, osteoporotic vertebral compression fracture (OVCF). The fracture causes severe pain, impedes respiratory function, lower the quality of life, and increases ...
Yuan-Zhe Jin, Jae Hyup Lee, Bin Xu, Minjoon Cho   +3 more
doaj   +1 more source

A randomized double-blind study of gallium nitrate compared with etidronate for acute control of cancer-related hypercalcemia.

, 1991
Hypercalcemia is a major source of morbidity and mortality in patients with cancer. Gallium nitrate and the bisphosphonate, etidronate, are new agents that have recently become available for treatment of this disorder.
P J O'Dwyer, R P Warrell, G Heller, W K Murphy, P Schulman   +4 more
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Smear Layer Removing and Pulp Dissolving Ability of Sodium Hypochlorite Mixed with Two Etidronate-Containing Irrigants in Continuous Chelation Technique

Applied Sciences
The study aimed to assess the effect of two etidronate-containing irrigants and EDTA on the ability of sodium hypochlorite (NaOCl) to remove the smear layer and dissolve organic tissues.
Anna Mikheikina, Ksenia Babina, Maria Polyakova, Vladlena Doroshina, Alexandr Zaytsev, Irina Makeeva, Nina Novozhilova   +6 more
doaj   +1 more source

The effects of divalent cations and substrates on the inhibition of human bone-type alkaline phosphatase activity by etidronate

, 2021
Bisphosphonates (BPs) inhibited alk aline phosphatase (ALP) activity by chelating Mg2+ (Mg) that i s necessary for ALP activation; however, many points are still unclear.
鈴木, 邦明, 吉村, 善隆, 島田, 英知, 山崎, 裕, 南川, 元   +4 more
core  

Long-term follow-up of therapy with intermittent etidronate disodium in paget's disease of bone

, 1985
A long-term trial of etidronate disodium therapy in 93 patients with Paget's disease of bone yielded generally favorable results. Treatment or retreatment was initiated for symptomatic Paget's disease with elevated serum alkaline phosphatase and urinary ...
Roy D. Altman, Altman, Roy D
core   +1 more source

Cyclical Etidronate Therapy for Prevention of Postmenopausal Bone Loss: A 1-Year Open-Label Follow-Up Study

, 2000
The objective of this study was to evaluate whether the pharmacological activity of cyclical etidronate therapy is sustained beyond the dosing period.
Blake, G M, I. Fogelman, Balena, R, Fogelman, I, R. J. M. Herd, G. M. Blake, R. Balena, Herd, R J M   +7 more
core   +1 more source