Nanoscopic Mapping of the Extracellular Space in Amyloid Plaque‐rich Cortex
The extracellular space and diffusion around amyloid plaques are examined using shadow imaging and single‐particle tracking. Increased diffusivity is found near plaques, extracellular matrix alterations, and plaque core penetrability that varies with amyloid phenotype.
Juan Estaún‐Panzano +11 more
wiley +1 more source
The role of the organs of internal secretion in the etiology of cancer
В. А. Сергеев
openalex +1 more source
Investigation into the Pancreatic Pathogenesis of SFTSV across Multiple Levels
A retrospective analysis revealed that 17.6% of severe fever with thrombocytopenia syndrome (SFTS) patients met the diagnostic criteria for clinically confirmed pancreatitis. Using human pancreatic organoids and murine models demonstrated that SFTSV exhibits a specific pancreatic tropism, leading to cell death and initiating a strong inflammatory ...
Xiaohan Liu +10 more
wiley +1 more source
Variceal Upper Gastrointestinal Bleeding: A Retrospective Cohort of 98 Cases, Historical Comparison, and Updated Management Algorithm. [PDF]
Barbu LA +11 more
europepmc +1 more source
Repurposing of Chemokine Antagonists for Combined Phase‐Resolved Spinal Cord Injury Treatment
Spinal cord injury (SCI) in mammals is accompanied by a massive cytokine storm in cerebrospinal fluid, mainly driven by CXCL1, IL‐6, and CCL2‐5. Sub‐acute phase is mostly associated with IL‐2, IL‐7, CCL22, and CX3CL1, whereas TNFα and IL17α permanently persists in CNS even weeks following SCI.
Alexey A. Belogurov Jr. +20 more
wiley +1 more source
Etiologic factors in developing sacrococcygeal pilonidal sinus disease in males; A cased-control study. [PDF]
de Kort J +6 more
europepmc +1 more source
Etiology, antimicrobial susceptibility profile of Staphylococcus spp. and risk factors associated with bovine mastitis in the states of Bahia and Pernambuco [PDF]
Carina C. Krewer +7 more
openalex +1 more source
IGF‐1 levels above 174.9 ng/mL were associated with better wound healing and lower postoperative inflammation. Higher IGF‐1 levels correlated with improved anal function at 7 and 14 days post‐surgery. ABSTRACT Background Anal fistula is a chronic condition characterized by an abnormal tract between the anal canal and perianal skin, often leading to ...
Zhijun Wu, Xuexue Yin, Jing Li
wiley +1 more source
Essential Updates 2023/2024: Recent Advances of Multimodal Approach in Patients for Gastric Cancer
ABSTRACT Gastric cancer remains a major global health burden, especially in East Asia. Recent years have brought significant advances in multimodal management, including surgery, perioperative chemotherapy, immunotherapy, and supportive care. This review summarizes key updates from 2023 to 2024, focusing on surgical innovations, perioperative systemic ...
Katsutoshi Shoda +3 more
wiley +1 more source

