Results 21 to 30 of about 1,422,201 (349)

An Integrated Pan-Cancer Analysis of 33 Human Cancers Reveals the Potential Clinical Implications and Immunotherapeutic Value of C-X-C Motif Chemokine Ligand 13

open access: yesFrontiers in Oncology, 2022
BackgroundC-X-C Motif Chemokine Ligand 13 (CXCL13) plays a crucial part in the pathogenesis of numerous lymphoproliferative disorders, inflammatory responses, and autoimmune diseases.
Huanyu Zhang   +11 more
doaj   +1 more source

Analysis Of Modern Views On The Etiology Of Dysgraphia [PDF]

open access: yes, 2018
The article considers the problem of dysgraphia as one of types of written speech disorders, studied by speech therapists, psychologists, neurophysiologists and neuropsychologists of different countries for more than hundred years, but still one of most ...
Zhuravlova, L. (Larysa)
core   +2 more sources

Aberrantly methylated-differentially expressed genes and pathways in colorectal cancer

open access: yesCancer Cell International, 2017
Background Methylation plays an important role in the etiology and pathogenesis of colorectal cancer (CRC). This study aimed to identify aberrantly methylated-differentially expressed genes (DEGs) and pathways in CRC by comprehensive bioinformatics ...
Jingwei Liu   +5 more
doaj   +1 more source

Association of mitochondrial homeostasis and dynamic balance with malignant biological behaviors of gastrointestinal cancer

open access: yesJournal of Translational Medicine, 2023
Mitochondria determine the physiological status of most eukaryotes. Mitochondrial dynamics plays an important role in maintaining mitochondrial homeostasis, and the disorder in mitochondrial dynamics could affect cellular energy metabolism leading to ...
Ao-ran Liu   +7 more
doaj   +1 more source

MiR-1539 and Its Potential Role as a Novel Biomarker for Colorectal Cancer

open access: yesFrontiers in Oncology, 2021
PurposeWe investigated microRNA (miR) 1539 as a potential biomarker for predicting the risk and pathobiological behavior of colorectal cancer (CRC).MethodsOur strategy consisted of analyzing 100 serum samples from 51 CRC patients, 49 healthy controls ...
Xueyang Cui   +14 more
doaj   +1 more source

Contemporary characteristics and outcomes in chagasic heart failure compared with other nonischemic and ischemic cardiomyopathy [PDF]

open access: yes, 2017
Background: Chagas’ disease is an important cause of cardiomyopathy in Latin America. We aimed to compare clinical characteristics and outcomes in patients with heart failure (HF) with reduced ejection fraction caused by Chagas’ disease, with other ...
Claudio R. Gimpelewicz   +17 more
core   +3 more sources

Key elements involved in Epstein–Barr virus-associated gastric cancer and their network regulation

open access: yesCancer Cell International, 2018
Background The molecular mechanism of Epstein–Barr virus (EBV)-associated gastric cancer (EBVaGC) remains elusive. A collection of molecular regulators including transcription factor and noncoding RNA (ncRNAs) may affect the carcinogenesis of EBVaGC by ...
Jing-jing Jing   +4 more
doaj   +1 more source

Protein folding disorders: Toward a basic biological paradigm [PDF]

open access: yes, 2010
Mechanistic 'physics' models of protein folding fail to account for the observed spectrum of protein folding and aggregation disorders, suggesting that a more appropriately biological paradigm will be needed for understanding the etiology ...
Rodrick Wallace
core   +3 more sources

HpSlyD inducing CDX2 and VIL1 expression mediated through TCTP protein may contribute to intestinal metaplasia in the stomach

open access: yesScientific Reports, 2017
Helicobacter pylori infection is the most important risk factor for gastric intestinal metaplasia (IM). Our previous study demonstrated that infection with H. pylori HpslyD-positive strains associated with IM.
Qiuping Li   +7 more
doaj   +1 more source

The changed endemic pattern of human adenovirus from species B to C among pediatric patients under the pressure of non-pharmaceutical interventions against COVID-19 in Beijing, China

open access: yesVirology Journal, 2023
Background Under the pressure of non-pharmaceutical interventions (NPIs) targeting severe acute respiratory syndrome coronavirus 2, the prevalence of human adenovirus (HAdV) was monitored before and after NPIs launched on Jan 24, 2020 in pediatric ...
Fangming Wang   +12 more
doaj   +1 more source

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