Randomised trial of intravenous thiamine and/or magnesium sulphate administration on erythrocyte transketolase activity, lactate concentrations and alcohol withdrawal scores [PDF]
Alcohol withdrawal syndrome (AWS) occurs in 2% of patients admitted to U.K. hospitals. Routine treatment includes thiamine and benzodiazepines. Laboratory studies indicate that thiamine requires magnesium for optimal activity, however this has not ...
Donogh Maguire +16 more
doaj +6 more sources
The relation between acute changes in the systemic inflammatory response and circulating thiamine and magnesium concentrations after elective knee arthroplasty [PDF]
Thiamine diphosphate (TDP) and magnesium are co-factors for key enzymes in human intermediary metabolism. However, their role in the systemic inflammatory response (SIR) is not clear.
Donogh Maguire +11 more
doaj +3 more sources
Bayesian inference of mixed Gaussian phylogenetic models [PDF]
Background Continuous traits evolution of a group of taxa that are correlated through a phylogenetic tree is commonly modelled using parametric stochastic differential equations to represent deterministic change of traits through time, while ...
Bayu Brahmantio +2 more
doaj +3 more sources
Reassessing Transketolase Assays: Methodological Considerations for Detecting Functional Thiamine Deficiency. [PDF]
Transketolase (TKT) activity provides a functional measure of thiamine status by integrating cofactor availability, enzyme abundance, and catalytic capacity. TKT catalyzes thiamine diphosphate (TDP)‐dependent reactions in the nonoxidative pentose‐phosphate pathway and requires magnesium for optimal activity.
Edwards KA.
europepmc +2 more sources
Relationship between refractive outcomes and quantitative retinal vascularization and severity of plus disease in eyes treated with intravitreal bevacizumab [PDF]
Purpose: The study aimed to investigate the relationship between refractive outcomes with the extent of retinal vascularization and severity of the plus disease in infants treated with intravitreal bevacizumab (IVB). Methods: Pre-IVB fundus images (PFIs),
Sadik Etka Bayramoglu, Nihat Sayin
doaj +2 more sources
Recurrent anorexia because of gastrointestinal beriberi in a home care patient. [PDF]
An elderly man with a history of unexplained anorexia and lethargy was diagnosed with gastrointestinal beriberi during home care. Empiric oral thiamine supplementation led to dramatic improvement, underscoring the importance of early recognition and treatment of thiamine deficiency.
Kawamura R +3 more
europepmc +2 more sources
Extraretinal Fibrovascular Proliferation in a Neonate Possibly Associated with an ESAM Gene Variant [PDF]
A female infant born with a gestational age of 35 weeks and birth weight of 2500 g was referred for ophthalmic examination on the second postnatal day. Bilateral venous dilatation and arterial tortuosity, severe extraretinal fibrovascular proliferation ...
Sadık Etka Bayramoğlu +5 more
doaj +2 more sources
Quantitative evaluation of the wide-field fundus photographs in eyes with severe stage 3 and stage 4A retinopathy of prematurity [PDF]
Background The aim of the study was to investigate the quantitative differences between severe stage 3 and stage 4A retinopathy of prematurity (ROP) by evaluating the pre-treatment fundus photographs.
Sadik Etka Bayramoglu +2 more
doaj +2 more sources
Thiamine deficiency in US veterans with obesity. [PDF]
Abstract Introduction Thiamine deficiency is common after bariatric surgery, but patients with obesity may be deficient in thiamine even before surgery. The purpose of this research was to determine the prevalence of thiamine deficiency in patients with obesity at a medical weight‐management clinic and assess the relationship between recent weight loss
Costello E, Kerns J.
europepmc +2 more sources
Dietary reference values for thiamin. [PDF]
Abstract Following a request from the European Commission, the EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) derived dietary reference values (DRVs) for thiamin (vitamin B1). The Panel considers that data from depletion–repletion studies in adults on the amount of dietary thiamin intake associated with the erythrocyte transketolase ...
EFSA Panel on Dietetic Products +29 more
europepmc +2 more sources

