Results 181 to 190 of about 89,048 (269)

ATGL sensitizes hepatocellular carcinoma cells to genotoxic drugs by modulating p53 acetylation/phosphorylation status. [PDF]

Cell Death Discov
Castelli S, De Cristofaro A, Desideri E, Salvi E, Ciccarone F, Ciriolo MR.   +5 more
europepmc   +1 more source

Transformation or Clonal Evolution? A Rare Case Report of Pulmonary Sarcomatoid Carcinoma Developing to Small Cell Lung Cancer

Thoracic Cancer, Volume 17, Issue 13, July 2026.
This is the first reported case of pulmonary sarcomatoid carcinoma undergoing conversion to small cell lung cancer. Genetic profiling of serial biopsies suggests clonal evolution or alternative transformation mechanisms. ABSTRACT Many cases of non‐small cell lung cancer (NSCLC) transforming to small cell lung cancer (SCLC) after targeted therapy have ...
Wen Jiang, Yuwei Zhang, Xingmei Li, Qi Si, Zhaohuan Ye, Youfeng Ma, Haitao Zhou, Jianwei Huang, Chao Zhang, Ge Zhang   +9 more
wiley   +1 more source

Optimal Duration of Adjuvant Platinum-Etoposide in High-Risk Merkel Cell Carcinoma. [PDF]

Medicina (Kaunas)
Brenner R, Edri HTF, Rouvinov K, Shani Shrem N, Meirovitz A, El-Saied S, Berezhnov I, Ievko A, Turaieva S, Fenig S, Abu Yasin N, Fenig E, Hussany S, Yakobson A, Shalata W.   +14 more
europepmc   +1 more source

Malignant craniopharyngiomas: Institutional experience and literature review

Brain Pathology, Volume 36, Issue 4, July 2026.
We report the second case of malignant craniopharyngioma with BAP1 and TP53 mutations. A literature review identified 44 cases of malignant craniopharyngiomas with a median overall survival of 6 months. Eighteen (41%) occurred in patients without any history of radiation, suggesting that mechanisms other than radiation have contributed to their ...
Thomas J. Auen, Isabella W. Zhang, Weiwei Zhang, Jordan M. Burr, Matthew L. Carda, James L. Wisecarver, Nicole Shonka, Jesse L. Cox, Sahara J. Cathcart, Allison Cushman‐Vokoun, Jie Chen   +10 more
wiley   +1 more source

Adebrelimab-based regimens as first-line treatment for ES-SCLC in specific populations: a real-world study in Chinese patients. [PDF]

Ther Adv Med Oncol
Jiang L, Wen J, Xu S, Meng L, Zhai N, Shao Z, Wu P, Zhao K, Kong L, Peng J, Huang Z, Meng X.   +11 more
europepmc   +1 more source

Plasma Protein Analysis for Biomarker Discovery in Lung Cancer Treated With Atezolizumab Combination Therapy in J‐TAIL‐2

Cancer Science, Volume 117, Issue 7, Page 1948-1960, July 2026.
BLURB FOR ETOC: The J‐TAIL‐2 study (NCT04501497) evaluated the efficacy and safety of atezolizumab, an anti‐programmed death‐ligand 1, plus chemotherapy in patients with non‐small cell lung cancer (NSCLC) and extensive‐stage small cell lung cancer (ES‐SCLC) in real‐world settings.
Yasushi Goto, Makoto Nishio, Kadoaki Ohashi, Atsushi Osoegawa, Eiki Kikuchi, Hideharu Kimura, Junichi Shimizu, Eisaku Miyauchi, Hiroshige Yoshioka, Ichiro Yoshino, Toshihiro Misumi, Yasutaka Watanabe, Nobuyuki Katakami, Akira Kisohara, Masafumi Yamaguchi, Hirotaka Kuroki, Masamichi Sugimoto, Hisao Ashimura, Misa Tanaka, Akihiko Gemma   +19 more
wiley   +1 more source

[Retracted] PTEN enhances G2/M arrest in etoposide‑treated MCF‑7 cells through activation of the ATM pathway. [PDF]

Oncol Rep
Zhang R, Zhu L, Zhang L, Xu A, Li Z, Xu Y, He P, Wu M, Wei F, Wang C.   +9 more
europepmc   +1 more source

Atezolizumab + Chemotherapy in Older Patients With Lung Cancer in Japan

Cancer Science, Volume 117, Issue 7, Page 1935-1947, July 2026.
OS (A–D) and PFS (E–H) in patients receiving (A/E) Atezo + CnP, (B/F) Atezo + PP, (C/G) Atezo + bev + CP, and (D/H) Atezo + CEa by age (≥ 70 years and < 70 years). aSaito R, et al. Presented at the 2024 American Society of Clinical Oncology Annual Meeting. Abstract 8092. Adapted with permission by the author.
Junichi Shimizu, Makoto Nishio, Kadoaki Ohashi, Atsushi Osoegawa, Eiki Kikuchi, Hideharu Kimura, Yasushi Goto, Eisaku Miyauchi, Hiroshige Yoshioka, Ichiro Yoshino, Toshihiro Misumi, Kozo Yoshimori, Kazuhiko Shibata, Takeshi Tsuda, Masahiro Seike, Takahiro Ota, Koichi Samata, Yuki Kobayashi, Misa Tanaka, Akihiko Gemma   +19 more
wiley   +1 more source

Case Report: Neuroendocrine-marker-negative high-grade neuroendocrine carcinoma mimicking squamous cell carcinoma: an underrecognized diagnostic pitfall. [PDF]

Front Immunol
He W, Tang Y, Li Y, Zhang J, You X, Wu Q.   +5 more
europepmc   +1 more source

Venetoclax‐Integrated Conditioning Strategies Prior to Allogeneic Hematopoietic Stem Cell Transplantation in Myeloid Neoplasms: A Scoping Review of Emerging Evidence

European Journal of Haematology, Volume 117, Issue 1, Page 117-131, July 2026.
ABSTRACT Allogeneic hematopoietic stem cell transplantation (allo‐HSCT) remains the only potentially curative therapy for many patients with high‐risk myeloid neoplasms, yet relapse and transplant‐related toxicity continue to limit durable benefit.
Mohammed Abdulgayoom, Amaal Gulied, Awni Alshurafa, Shehab F. Mohamed, Mohamed A. Yassin, Afraa Fadul   +5 more
wiley   +1 more source