Results 71 to 80 of about 89,048 (269)
Background: Plants are an important origin of natural substances that the raw material for various pharmaceutical and therapeutic applications due to the presence of phytochemicals, such as alkaloids. Alkaloids, which are found in different plant species,
Anna Petruczynik +5 more
doaj +1 more source
Etoposide. Conformational and Hydration Features
The proton chemical shifts of the anticancer agent etoposide in CD3OD, dry CDCl3 and ‘wet’ CDCl3 were determined and all proton resonances were assigned.
Zhang, Kangling +4 more
core +1 more source
ABSTRACT Treatment of sarcoma includes high‐dose anthracyclines, which can cause cardiotoxicity. This study assesses the correlation of cardiac biomarkers and echocardiographic parameters on asymptomatic cardiotoxicity in sarcoma patients treated with anthracyclines.
Elissa A. S. Polomski +6 more
wiley +1 more source
Occupational rhinosinusitis due to etoposide, an antineoplastic agent
OBJECTIVE: This paper reports a rare case of an occupational hypersensitivity reaction to an antineoplastic agent. METHODS: This is a clinical case report of a 45-year-old nurse who developed throat irritation and chronic nasal congestion followed by ...
Harald W Meyer, Per Stahl Skov
doaj +1 more source
Phase I clinical and pharmacokinetic study of oral etoposide phosphate.
PURPOSE To determine the bioavailability (F) and the pharmacokinetic profile of both etoposide and its prodrug, etoposide phosphate, after oral and intravenous administration of etoposide phosphate, and to determine the maximum-tolerable dose (MTD) of ...
M De Fusco +9 more
core +1 more source
A compendium of extracellular vesicle biogenesis inhibitors: From bench to bedside
This review explores a decade of research on extracellular vesicles (EVs), detailing their biogenesis and roles in health and disease. It emphasizes EVs' relevance for potential medical applications covering various conditions such as cancer, neurodegeneration, inflammation, and infectious diseases, bridging experimental findings with clinical ...
Stefano Vecchione +2 more
wiley +1 more source
Hypersensitivity reaction to etoposide. A case report [PDF]
M. Mullera Martí +3 more
doaj +1 more source
Purpose: The pharmacokinetics of etoposide were studied in cancer patients with brain metastases treated with high-dose etoposide in order to determine if the pharmacokinetics were altered by the use of dexrazoxane as a rescue agent to reduce the ...
Schroeder, Patricia E. +5 more
core +1 more source
Extracellular vesicles play pivotal roles in both healthy hematopoiesis and hematologic malignancies. They not only regulate hematopoietic stem cell fitness but also drive cancer progression and drug resistance. Their clinical potential spans from serving as non‐invasive biomarkers to acting as innovative therapeutic platforms and drug delivery ...
Fengyu Chen +5 more
wiley +1 more source
Construction and mechanism of a small cell lung cancer cell line resistant to EP chemotherapy scheme
Objective To construct the etoposide (VP-16) combined with cisplatin (DDP) chemotherapy scheme (EP chemotherapy scheme) resistant small cell lung cancer (SCLC) cell line H446/EP and to identify the drug resistance characteristics and explore the ...
LIU Mingpu +3 more
doaj +1 more source

