Results 141 to 150 of about 125,560 (309)

The EU Party System after Eastern Enlargement [PDF]

open access: yes, 2005
From 1953 on, a party system of the European Union has been build up with, at the end,\ud some 6 or 7 distinct and more or less cohesive parties acting in parliament and beyond.
Schmitt, Hermann, Thomassen, Jacques
core   +3 more sources

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Sizing It Up: Labor Migration Lessons of the EU Enlargement to 27 [PDF]

open access: yes
While economists were pointing out the advantages of the EU enlargement, politicians and policymakers were raising grave concerns about the significant political and economic differences between the newcomer states (EU12) and the "old Europe" of EU15 ...
Constant, Amelie F.
core  

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

The impact of EU enlargement on migration flows [PDF]

open access: yes, 2003
This document is a report commissioned by the Home Office in order to assess the magnitude of potential migration flows to the UK after the enlargement of the European Union (EU).
Casanova, M.   +4 more
core  

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

European Integration in Trade and FDI: A Dynamic Perspective [PDF]

open access: yes
EU-Erweiterung, Europäische Integration, Direktinvestition, Europäische Wirtschafts- und Währungsunion, Osteuropa, EU enlargement, European integration, Foreign direct investment, European Economic and Monetary Union, Eastern ...
Peter Egger
core  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

ECB Decision-making and the Status of the Eurogroup in an Enlarged EMU [PDF]

open access: yes
This paper analyses the link between forthcoming EU enlargement and selected aspects of EU institutional reforms, namely decision making rules in the European Central Bank and the status of the Eurogroup. It argues that some earlier arguments calling for
Wojciech Paczynski
core  

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