Results 241 to 250 of about 125,560 (309)

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky, Cara Joyce, H. Jeremy Bockholt, Paul A. Rudnick, William H. Adams, Fiona McAllister, Justin W. Smock, Michael A. Newton, Jane S. Paulsen   +8 more
wiley   +1 more source

Dogs with advanced myxomatous mitral valve disease have evidence of gastrointestinal bacterial translocation and systemic inflammation. [PDF]

PLoS One
Jugan MC, Rands GA, Steiner JM, Cernicchiaro N, Tanner MC, Novotny LM.   +5 more
europepmc   +1 more source

In‐Depth Profiling Highlights the Effect of Efgartigimod on Peripheral Innate and Adaptive Immune Cells in Myasthenia Gravis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is an autoimmune disorder characterized by antibody‐mediated complement activation. Efgartigimod, a neonatal Fc receptor (FcRn) antagonist, is approved for treating generalized MG (gMG). However, its modulatory effects on upstream innate and adaptive immune cells remain largely unexplored.
Lei Jin, Liu Dong, Ying Wang, Dingxian He, Chong Yan, Jianying Xi, Haoqin Jiang, Yu Shi, Ming Guan, Chongbo Zhao, Jie Song, Sushan Luo   +11 more
wiley   +1 more source

Development of Oil Industry in Poland in the Context of the European Union. [PDF]

Foods
Bełdycka-Bórawska A, Bórawski P, Holden L, Rokicki T.   +3 more
europepmc   +1 more source

Vacuum-assisted excision followed by minimal access surgery for a large fibroadenoma: lessons from a hybrid approach - a case report. [PDF]

Int J Surg Case Rep
Karamanliev M, Shoshkova M, Petrova S, Dimitrov D.   +3 more
europepmc   +1 more source

Use of pimobendan in cats: a practical evidence-based review. [PDF]

J Feline Med Surg
Gordon SG, Saunders AB, Wesselowski S, Malcolm EL, Watson A.   +4 more
europepmc   +1 more source

Identification of a novel KISS1R (GPR54) gene variant (c.505+2T>G) in a patient with congenital hypogonadotropic hypogonadism: A case report and literature review. [PDF]

Exp Ther Med
Menekse B, Ucgul E, Bakir A, Hepsen S, Ozturk Unsal I, Kizilgul M, Araki T, Cakal E.   +7 more
europepmc   +1 more source

<i>Arion vulgaris</i> pedal epithelium displays fluorescence patterns consistent with uptake of&nbsp; <i>Nicotiana tabacum</i> extracellular dye-labeled vesicles <i>ex vivo</i>. [PDF]

MicroPubl Biol
Liegertová M, Iljučoková M, Smejkal J, Malý J, Kocholatá M.   +4 more
europepmc   +1 more source

Risk assessment for Brucella suis biovar 2 in Danish pigs. [PDF]

Porcine Health Manag
Alban L, Dresling A, Poulsen MK.
europepmc   +1 more source

A Positive Explanation of EU Enlargement. [PDF]

BROU, Daniel, RUTA, Michele
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