Results 141 to 150 of about 467,723 (245)

Roles and functioning of the European Union National Ethics Councils (NECs): a cross-sectional study. [PDF]

BMC Med Ethics
Koporc Z, Sikorska E, Puljak L.
europepmc   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

How the hybrid rules of free and paid medical care affect the post-socialist health system. [PDF]

BMC Health Serv Res
Shishkin S, Sheiman I, Potapchik E, Sazhina S, Vlassov V.   +4 more
europepmc   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

European citizens' support for humanitarian aid funded by the EU: a secondary analysis of Eurobarometer data from the 27 EU Member States. [PDF]

Lancet Reg Health Eur
Ktenidis G, Vardavas CI, Filippidis FT, Orfanos P, Lagiou P.   +4 more
europepmc   +1 more source

Collecting the EU's Regional Funds

, 2012
One of the key funding mechanisms of the European Union is the Regional Policy, which helps to implement infrastructure projects across the 27 member states. Money is allocated along a set of objectives and disbursed at the regional level, by 60-odd managing bodies. But who is getting the money and what is it really spent on?
openaire   +1 more source

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

Molecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

European funds and firm performance: evidence from a natural experiment. [PDF]

Small Bus Econ (Dordr)
Mesquita J, Pereira Dos Santos J, Tavares J.   +2 more
europepmc   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Validity and reliability of the Bangla version of the European health literacy survey questionnaire (HLS-EU-Q16) for university students. [PDF]

BMC Public Health
Sinthia MK, Ferdous MZ, Islam MS, Pramanik N, Bhuiyan MH.   +4 more
europepmc   +1 more source