Results 91 to 100 of about 1,867,653 (281)

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Intelligent Region Management = Intelligent Absorption of EU funds [PDF]

open access: yes
Effective institutions and public administration is a key factor in designing and implementing the growth policy and the economic and social development.
Cornelius Pylak
core  

FACTORS INFLUENCING THE ABSORPTION OF EU FUNDS FOR THE LAST MEMBERS STATES ECONOMY IN EUROPEAN UNION [PDF]

open access: yesAnalele Universităţii Constantin Brâncuşi din Târgu Jiu : Seria Economie
The absorption of European funds is widely seen as a way of economic growth and job creation through payments made from the EU budget as co-financing for eligible projects granted to EU member states. The article presents a study on the absorption of
SUCIU TEODORA MARIA
doaj  

EU Structural Funds in the Baltic Countries-Useful or Harmful. Euroopa Liidu struktuurifondid Balti riikides- kasulikud või kahjulikud?

open access: yesEesti Majanduspoliitilised Väitlused, 2016
The current article is focused on the role of financial assistance from the European Union in the budgets of the three Baltic countries. They all have seriously benefitted from the support of EU structural funds, which have reached close to five per cent
Urmas Varblane
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Ireland: An Example Of Best Practices In The Utilization of EU funds [PDF]

open access: yes
Ireland holds the story of a successful evolution from the moment of its accession to the European Union up to the present day, achieving an impressive economic transformation that repositioned the country in the hierarchy of developed EU member states ...
Amalia Nicoleta Coman, Paul Coman
core  

Assessing the Impact of European Funds Absorption in Romania in the Context of Financial Stability [PDF]

open access: yesOvidius University Annals: Economic Sciences Series
The impact of the absorption of European funds in Romania, in the context of financial stability, is a complex subject, approached with the aim of balancing the associated benefits and risks.
Oana Oprisan   +1 more
doaj  

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Additionality and regional development: are EU Structural Funds complements or substitutes of national Public Finance? [PDF]

open access: yes
This paper deals with the effects of the transfer of additional funds on the real economy of recipient countries, in particular the European Member States.
Silvia Vignetti   +3 more
core  

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