Results 181 to 190 of about 1,875,273 (281)

Underutilised Crops for a Sustainable Future: Promoting Resilience and Nutrition in Global Food Systems. [PDF]

open access: yesPhysiol Plant
Moreira D   +15 more
europepmc   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

open access: yesFEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos   +9 more
wiley   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

External validation and refinement of the Psychosis Polyrisk Score to detect individuals at clinical high risk for psychosis. [PDF]

open access: yesBMJ Ment Health
Stefanelli R   +70 more
europepmc   +1 more source

Smaller is better: nanobodies meet NMR

open access: yesFEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

open access: yesFEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Collecting the EU's Regional Funds

open access: yes, 2012
One of the key funding mechanisms of the European Union is the Regional Policy, which helps to implement infrastructure projects across the 27 member states. Money is allocated along a set of objectives and disbursed at the regional level, by 60-odd managing bodies. But who is getting the money and what is it really spent on?
openaire   +1 more source

EUPopLink Country report - Ireland. [PDF]

open access: yesOpen Res Eur
Mc Donnell R, Fanoulis E.
europepmc   +1 more source

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