Results 131 to 140 of about 32,658 (263)

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Imported zoonotic Ancylostoma ceylanicum and Ancylostoma braziliense infections in a cat in Romania. [PDF]

Parasit Vectors
Mitrea IB, Cernea MS, Ionică AM, Cârstolovean AS, Hii SF, Zendejas-Heredia PA, Huggins L, Colella V, Mihalca AD.   +8 more
europepmc   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Physiological responses to emotional video stimuli: ECG, EDA, and temperature data. [PDF]

Data Brief
Pataca AO, Al-Jumaili S, Coelho PJ, Garcia NM, Albuquerque C, Pires IM.   +5 more
europepmc   +1 more source

The use of EU funds in Slovakia

Strategic Management, 2015
The paper investigates how funds are allocated by the European Union and how they are used in the Slovak Republic. The paper concentrates on utilizing funds in two regions: Trnava self-governing region and Presov self-governing region, in two periods, namely 2004-2006 and 2007-2013. The conclusions define some negative issues in the process of applying
openaire   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Identifying the Thermodynamic Driving Force of Metal Extraction by Hydrophobic Eutectic Solvents. [PDF]

ChemSusChem
Vaz ICM, Saldanha Pinheiro M, Olea F, Cirillo L, Mannucci G, Busato M, D'Angelo P, Santos R, Bastos M, Santos LMNBF, Coutinho JAP, Schaeffer N.   +11 more
europepmc   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Access to Medicines in Bulgaria and North Macedonia: Legislative, Pricing, and Reimbursement Perspectives. [PDF]

Pharmacy (Basel)
Todorova A, Miceva D, Ivanova M, Kazakova T, Angelovska B.   +4 more
europepmc   +1 more source

Call for more EU funding [PDF]

Nature, 2010
openaire   +1 more source