Results 71 to 80 of about 3,363,783 (274)
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
The idea of establishing a separate fund within the EU arose during the COVID-19 crisis. It was assumed that after the temporary closure of key economic sectors, an additional flow of money would be needed to stimulate economic activity again.
Mirosław Piotrowski
doaj +1 more source
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Immunity of EU Institutions in Judicial Proceedings in the EU Member States
By virtue of Protocol on the Privileges and Immunities of the European Union and its institutions, the latter are granted immunity of jurisdiction and immunity of enforcement. However, such an immunity is an exception in any procedural law.
Jorg Sladič
doaj +1 more source
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Crossing borders in higher education? A comparative case study at the intersections of EU regional and higher education policies [PDF]
BEven though the European Union’s policy for regional development addresses higher education institutions, there is little research on the relationship between EU regional and higher education (HE) policies.
Alina FELDER
doaj
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Rule in the New European Union
This article suggests that the economically activist tendencies of the European Union are not just a temporary response to exogenous crises, but part of a long-term transformation of the EU into a governance structure that is increasingly equipped for ...
Floris de Witte
doaj +1 more source
Growth without development: institutional barriers to convergence in EU candidate states [PDF]
This research analyzes the effect of institutions on economic growth in eight EU candidate transition countries, combining quantitative (β-convergence models) and qualitative (integration maturity framework) methodologies.
Dzenita Siljak, Kristian L. Nielsen
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source

