Results 41 to 50 of about 4,638,258 (384)

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

The EU's Accession to the European Convention on Human Rights: An International Law Perspective [PDF]

, 2015
Article 6(2) of the Treaty on European Union establishes that the Union “shall accede to the European Convention for the Protection of Human Rights and Fundamental Freedoms.” In early 2013, negotiators of the 47 Council of Europe member states and the ...
Odermatt, J.
core  

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source

Area of Freedom, Security and Justice in Confrontation With Legal Populism: The Polish Example of Judiciary Crisis

Politeja
Ensuring an Area of Freedom, Security, and Justice for EU citizens is one of the most important goals of the European Union. Achieving this goal constitutes a significant challenge, as according to the TFEU (Treaty on the Functioning of the European ...
Brygida Kuźniak, Agata B. Capik
doaj   +1 more source

Common Agricultural Policy in the EU and the Ministry of Agriculture in the Czech Republic with a Focus on Environmental and Consumer Protection and Support for Smes

EU agrarian Law, 2022
The common agricultural policy and the implementation of this policy represent a relatively high part of the costs in the EU budget. From this point of view, the content of the common agricultural policy is important to meet both the primary objective ...
Jurčík Radek
doaj   +1 more source

Platforms, Power, and the Antitrust Challenge: A Modest Proposal to Narrow the U.S.-Europe Divide [PDF]

, 2019
Big platforms dominate the new economy landscape. Colloquially known as GAFA [Google, Amazon, Facebook, and Apple] or FAANG [Facebook, Amazon, Apple, Netflix, and Google], the high tech big data companies are charged with using the power of their ...
Fox, Eleanor M.
core   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

From the Pandemic to the War: The EU Fiscal Response to Russia's Aggression of Ukraine, the Legacy of NGEU, and the Challenge to “Promote the General Welfare”

AJIL Unbound
As the European Union (EU) was slowly re-emerging from the COVID-19 pandemic, it faced another unprecedented shock: Russia's large-scale military invasion of Ukraine.
Federico Fabbrini
doaj   +1 more source

Implementation of Waste Management Program: Case Study of Self–Government Unit of Bački Petrovac in Serbia

EU agrarian Law, 2022
As part of the negotiations for EU accession, the Republic of Serbia through Chapter 27 (Poglavlje 27 u Srbiji: Napredak pod ključem(1)), has begun the process of establishing a waste management system and adapting it to the goals and acquis ...
Valenćiková Marina
doaj   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source