Results 81 to 90 of about 556,266 (299)

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

Economic Complexity – High Technological Product Nexus for Selected EU Countries: Panel Data Analysis

open access: yesScientific Annals of Economics and Business
Making high-tech goods is the main requirement for scoring highly on the economic complexity index (ECI). Importing high-tech goods can help nations that lack access to these entire resources boost their production capacity.
Ibrahim Ozayturk
doaj   +1 more source

Portuguese Foreign Direct Investments Inflows: An Empirical Investigation [PDF]

open access: yes
This paper examines the link between Portugal’s foreign direct investment (FDI) inflows from European Union (EU-15) countries using panel data and country specific variables for the period 1996-2006.
Horácio Faustino, Nuno Carlos Leitão
core  

Housing Satisfaction, Homeownership and Housing Mobility: A Panel Data Analysis for Twelve EU Countries [PDF]

open access: yesSSRN Electronic Journal, 2006
We investigate the determinants of housing satisfaction in twelve EU countries. To do so, we use panel data covering the period 1994-2001, which allows us to control for individual heterogeneity. We carry out separate estimates on the determinants of housing satisfaction for homeowners and for renters and observe that: i) the tenure status is critical ...
openaire   +2 more sources

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

open access: yesMolecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy   +9 more
wiley   +1 more source

Assessment of a decontamination process for hydrocyanic acid in linseed intended for use in animal feed

open access: yesEFSA Journal, 2017
Following a request from the European Commission, the EFSA Panel on Contaminants in the Food Chain (CONTAM) provided a scientific opinion on the assessment of a decontamination process for the enzymatic treatment and subsequent heating of linseed, in ...
EFSA Panel on Contaminants in the Food Chain (CONTAM)   +24 more
doaj   +1 more source

Back on Track?: Savings Puzzles in EU-Accession Countries [PDF]

open access: yes
After the collapse in the early years of transition, saving rates in many EU-accession countries have recovered and remained stable during recent years. This may indicate that the transformation process has come to an end with regard to savings.
Mechthild Schrooten, Sabine Stephan
core  

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser   +14 more
wiley   +1 more source

Economic determinants of citizens’ support for the European Union [PDF]

open access: yes
We investigate the determinants of public support for EU membership using a panel of fifteen countries over the 1974 - 2008 period. The results indicate that increases in inflation and unemployment rate generate a decrease in support for EU membership ...
Carlos Gama Nogueira   +1 more
core  

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