Results 81 to 90 of about 92,164 (300)

Safety and efficacy of Manganese chelates of lysine and glutamic acid as feed additive for all animal species

open access: yesEFSA Journal, 2020
Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the safety and efficacy of manganese chelates of lysine and glutamic acid (Manganese‐LG) as nutritional feed additive for all animal species.
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP)   +21 more
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Assessment of a decontamination process for hydrocyanic acid in linseed intended for use in animal feed

open access: yesEFSA Journal, 2017
Following a request from the European Commission, the EFSA Panel on Contaminants in the Food Chain (CONTAM) provided a scientific opinion on the assessment of a decontamination process for the enzymatic treatment and subsequent heating of linseed, in ...
EFSA Panel on Contaminants in the Food Chain (CONTAM)   +24 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Bootstrap panel Granger-causality between government spending and revenue in the EU [PDF]

open access: yes
Using bootstrap panel analysis, allowing for cross-country correlation, without the need of pre-testing for unit roots, we study the causality between government revenue and spending for the EU in the period 1960-2006.
António Afonso, Christophe Rault
core  

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Oil Price and Stock Prices of EU Financial Companies: Evidence from Panel Data Modeling

open access: yesEnergies, 2019
Crude oil is an indispensable resource for the world economy and European Union (EU) countries are strongly dependent on oil imports. In a framework defined by generally positive correlations between oil and stock prices, the paper investigates the ...
Alexandra Horobet   +3 more
doaj   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

EU Enlargement and Migration: Scenarios of Croatian Accession [PDF]

open access: yesRomanian Journal of European Affairs, 2013
This paper analyzes the possible incidence of pending Croatian EU accession that is to take place on the 1st of July 2013, on the labour migration from Croatia to the European Union. We apply panel data estimators using the data on emigration from 18 EU
Wadim Strielkowski   +2 more
doaj  

Is Global Competitiveness Speeding Up the Growth in the EU? A Panel Data Analyis

open access: yesStudia Universitatis Vasile Goldis Arad, Seria Stiinte Economice, 2018
The paper documents the impact of global competitiveness on economic growth in the EU Member States. In a panel data approach, for a time span of 10 years (2008- 2017), a validated influence of Global Competitiveness Index on annual rate of GDP in the EU
Neagu Olimpia
doaj   +1 more source

Home - About - Disclaimer - Privacy