Results 221 to 230 of about 5,086,136 (302)

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

FEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey, Miriam Livier Llamas‐García, Gabriela M. Montero‐Morán, Leticia Santos, Samuel Lara‐González   +4 more
wiley   +1 more source

Role of Family Medicine in Integrative Prevention and Management of Oncologic Diseases in Romania. [PDF]

Healthcare (Basel)
Leru PM, Anton VF, Cercel C, Eremia IA, Cazacu SM, Neagoe CD.   +5 more
europepmc   +1 more source

Salmonella enterica serovar typhi limits the potency of typhoid toxin and ADP‐ribosylating toxin AB to establish a persistent infection

FEBS Open Bio, EarlyView.
The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez, Juliette K. Tinker, Teresa Frisan, Taj Azarian, Ken Teter   +4 more
wiley   +1 more source

Representativeness and external comparability of the InGef research database for epidemiological studies in Germany. [PDF]

BMC Health Serv Res
Alibone M, Ludwig M, Obermüller D, Pawlowska-Phelan D, Norris R, Jacob J.   +5 more
europepmc   +1 more source

A minimal cellulosome‐like system in Cellulosilyticum lentocellum

FEBS Open Bio, EarlyView.
Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan, Amias Alstrom‐Moore, Gary W Black   +2 more
wiley   +1 more source

Urban PM_0.2 Affects Astrocytes by Inducing Xenobiotic and Oxidative Stress Responses. [PDF]

Mol Neurobiol
Saveleva L, Afonin A, Ivanova M, Sima M, Krejcik Z, Malm T, Jalava PI, Rössner P, Kanninen KM.   +8 more
europepmc   +1 more source

Cell surface CD11c as a neutrophil aging marker molecule

FEBS Open Bio, EarlyView.
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki, Fahd Alhamdan, Erik Malm, Marie Bermudez, Samuel Y. Kim, Koichi Yuki   +5 more
wiley   +1 more source

The communication of science within the framework of European Union-funded research projects: Exploring practitioners' experiences and perceptions. [PDF]

Public Underst Sci
Arboledas-Lérida L.
europepmc   +1 more source

Evaluating GenAI‐produced feedback on undergraduate bioscience essays against good higher education feedback practice

FEBS Open Bio, EarlyView.
This pilot study investigates the potential of Generative AI to provide formative feedback to students. ChatGPT was prompted to provide feedback on Year 1 Bioscience essays, which were evaluated against established good feedback practices. GenAI‐authored feedback had useful elements, but was limited in scope. GenAI may have potential to provide instant,
Annabel Court, Nigel Francis, Andrew Shore, Stephen Rutherford   +3 more
wiley   +1 more source

Factors associated with intracerebral hemorrhage in confirmed cerebral amyloid angiopathy. [PDF]

Alzheimers Dement
Chaachou-Charradi A, Burgueño-García I, Camacho-Soriano J, Moliné-Marimón T, Zagrean N, Ramón Y Cajal-Agüeras S, Rábano-Gutiérrez A, Martínez-Sáez E, Hernández-Guillamon M.   +8 more
europepmc   +1 more source