Results 81 to 90 of about 227,974 (244)
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Ukraine and the EU: Prospects and Challenges on the Road to Integration
Acta de Historia & Politica: Saeculum XXIThis article examines Ukraine’s journey toward European Union integration, focusing on the prospects and challenges that lie ahead. Ukraine’s desire for EU membership represents not only a strategic shift but also a complex transformation requiring ...
Анна Соловйова +1 more
doaj +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Values of Wildlife in the Policy of EU and Ukraine
, 2019 The aim of the article is to study the implementation of wildlife values into the environmental policy of European Union and Ukraine. The research methodology is based on a comparative analysis of the activities of the EU and Ukraine in the protection of wildlife. The study has introduced the essence of the terms "wildlife" and "value of wildlife." The
openaire +2 more sources
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Unravelling nature's values in EU agricultural policy: A critical discourse analysis
People and NatureAgriculture plays a dual role as both a key driver and a potential solution for biodiversity loss. Farmers, holding a variety of values related to nature, are therefore key actors in biodiversity conservation.
Iven Froese, Lasse Loft
doaj +1 more source
Constitutionalism without principle: Article 2 TEU and the doctrinal construction of EU values
European Law OpenHalf a century ago, Martin Shapiro discovered that European constitutional scholarship was stuck at a stage of ‘constitutional law without politics’, presenting the EU ‘as a juristic idea; the written constitution as a sacred text; the professional ...
Martijn van den Brink
doaj +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source