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HP1γ associates with euchromatin and heterochromatin in mammalian nuclei and chromosomes
Cytogenetic and Genome Research, 2000Heterochromatin protein 1 (HP1) is a nonhistone chromosomal protein, first identified in <i>Drosophila,</i> that plays a dose-dependent role in gene silencing. Three orthologs, HP1α, HP1β, and HP1γ, have been characterized in mammals. While HP1α and HP1β have been unambiguously localized in heterochromatin by immunocytochemical methods ...
J.-C. Courvalin, E. Minc, B. Buendia
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Loss of DNA and euchromatin in senescing leaf cells of Allium
Mechanisms of Ageing and Development, 1982The leaves of the chive, Allium schoenoprasum, have an average life-span of 53 days, then they fade from top to bottom, in the same sequence as cells originated. Starting during the adult phase, the amount of DNA per nucleus decreases significantly. Nuclei of senescent cells exhibit about 15% less DNA than nuclei of juvenile cells. Electron-microscopic
Walter Nagl, Achim Drumm
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Regulating genes by packaging domains: bits of heterochromatin in euchromatin?
Trends in Genetics, 1993which a variegating gene is inactivated and the frequency with which it is incorporated within cytologically visible heterochromatin 16,17, and also by changes at the molecular level in the chromatin structure of variegating loci TM. While there is evidence that some variegating loci are inactivated as a consequence of DNA loss, due to differential ...
Christopher D. Shaffer +2 more
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Heterochromatin and Euchromatin-Organization, Boundaries, and Gene Regulation
2011A functional genome is carefully orchestrated into different chromosomal domains of gene activity and noncoding structural domains, such as centromeres. Histone modifications and DNA methylation are examples of epigenetic mechanisms, which determine if a chromosomal region will be in an active “euchromatin” or an inactive “heterochromatin” state.
Annelie Strålfors, Karl Ekwall
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Nature Structural &Molecular Biology, 2012
Valentina Migliori +16 more
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Valentina Migliori +16 more
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