The Journal of Physiology, EarlyView.Abstract figure legend AC: adenylyl cyclase, APT: adenosine triphosphate, AMP: adenosine monophosphate, cAMP: cyclic adenosine monophosphate, PDE: phosphodiesterase, PKA: protein kinase A, PPT: protein phosphatase, P: phosphorylation, RyR: ryanodine receptor, SERCA: sarcoplasmic/endoplasmic reticulum Ca2+‐adenosine triphosphatase, SR: sarcoplasmic ...
Moritz Linder +4 more
wiley +1 more source
Mathematical model of the zebrafish ventricular cardiomyocyte action potential and calcium transient
The Journal of Physiology, EarlyView.Abstract figure legend This study presents the development and validation of the first biophysically detailed computational model of the zebrafish ventricular action potential (AP). The model is based on a human cardiomyocyte framework and reparameterized using published and newly generated patch‐clamp recordings of zebrafish ionic currents.
Ludovica Cestariolo +5 more
wiley +1 more source
SpatialCNS-PBPK: An R/Shiny Web-Based Application for Physiologically Based Pharmacokinetic Modeling of Spatial Pharmacokinetics in the Human Central Nervous System and Brain Tumors. [PDF]
CPT Pharmacometrics Syst PharmacolWickramasinghe CD, Kim S, Li J.
europepmc +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend Ephaptic phenomena in a high‐resolution model of the cardiac intercalated disc. Meshed representation of a tortuous intercalated disc that was generated based on electron and super‐resolution microscopy data. Na+ channels (red) and gap junctions (green) are heterogeneously distributed, with additional regions of reduced ion ...
Ena Ivanovic +4 more
wiley +1 more source
Bionic Inner-Tapered Energy Absorption Tube Featuring Progressively Enhanced Fold Deformation Mode. [PDF]
Biomimetics (Basel)Zhang S +7 more
europepmc +1 more source
Three‐Dimensional Analytical Model of a Free‐Standing Square Rocking Column
Earthquake Engineering &Structural Dynamics, Volume 55, Issue 8, Page 1710-1727, 10 July 2026.ABSTRACT A three‐dimensional analytical two‐degree‐of‐freedom (2DOF) model is developed to describe the bounded rocking response of free‐standing rigid square columns subjected to bidirectional seismic excitation. The formulation extends Housner's classical planar theory by deriving the full three‐dimensional equations of motion for a column ...
Dimitra Adamopoulou +1 more
wiley +1 more source
Dual-Functioning Metal-Organic Frameworks: Methotrexate-Loaded Gadolinium MOFs as Drug Carriers and Radiosensitizers. [PDF]
ChemistryKaraca B +9 more
europepmc +1 more source
Stochastic control of influenza spread: A Lévy-driven SDE and branching process approach. [PDF]
Infect Dis ModelMohammad KM, Khan T, Kamrujjaman M.
europepmc +1 more source
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