Results 161 to 170 of about 1,232 (217)

Solving Stochastic Climate‐Economy Models: A Deep Least‐Squares Monte Carlo Approach

open access: yesMathematical Finance, EarlyView.
ABSTRACT Stochastic versions of recursive integrated climate‐economy assessment models are essential for studying and quantifying policy decisions under uncertainty. However, as the number of state variables and stochastic shocks increases, solving these models via deterministic grid‐based dynamic programming (e.g., value‐function iteration/projection ...
Aleksandar Arandjelović   +4 more
wiley   +1 more source

Likelihood Estimation for Stochastic Differential Equations with Mixed Effects

open access: yesScandinavian Journal of Statistics, EarlyView.
ABSTRACT Stochastic differential equations provide a powerful tool for modelling dynamic phenomena affected by random noise. When time series are observed for several experimental units, it is often the case that some of the parameters vary between the individual experimental units.
Fernando Baltazar‐Larios   +2 more
wiley   +1 more source

In silico modelling of multi‐electrode arrays for enhancing cardiac drug testing on hiPSC‐CM heterogeneous tissues

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Schematic overview of the experimental and computational framework for investigating hiPSC‐CM electrophysiology with MEA systems. The MEA‐based model integrates experimental data with phenotype‐specific ionic models and tissue‐level heterogeneity.
Sofia Botti   +2 more
wiley   +1 more source

Enhanced FPGA-based smart power grid simulation using Heun and Piecewise analytic method. [PDF]

open access: yesSci Rep
Gul U   +5 more
europepmc   +1 more source

Electrodiffusion in cardiac intercalated disc nanostructures alters cell–cell action potential transmission via ephaptic coupling: A model study

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Ephaptic phenomena in a high‐resolution model of the cardiac intercalated disc. Meshed representation of a tortuous intercalated disc that was generated based on electron and super‐resolution microscopy data. Na+ channels (red) and gap junctions (green) are heterogeneously distributed, with additional regions of reduced ion ...
Ena Ivanovic   +4 more
wiley   +1 more source

A microstructurally motivated framework to study autoregulation in the coronary circulation

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend A microstructurally motivated framework was constructed to simulate coronary autoregulation in symmetrically bifurcating trees at three myocardial depths: subepicardial (subepi), midwall and subendocardial (subendo). Wall mechanics of individual vessels are governed by a constrained‐mixture model, incorporating elastin, collagen ...
Matthew J. Eden   +8 more
wiley   +1 more source

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