Results 161 to 170 of about 5,879,476 (365)

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

Molecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser, Florian Krumbach, Eyleen Corrales, Geoffroy Andrieux, Christian Preisinger, Franziska Liss, Alexandra Golzmann, Melanie Boerries, Kerstin Becker, Ruth Knüchel, Stefan Garczyk, Bernhard Lüscher   +11 more
wiley   +1 more source

The Asylums of Europe [PDF]

The Boston Medical and Surgical Journal, 1880
n ...
openaire   +2 more sources

Europeans in the Indian Services [PDF]

, 1924

openalex   +1 more source

Germline variants in CDKN2A wild‐type melanoma prone families

Molecular Oncology, EarlyView.
Among melanoma‐prone families, wild‐type for CDKN2A and CDK4, some have pathogenic variants in genes not usually linked to melanoma. Furthermore, rare XP‐related variants and variants in MC1R are enriched in such families. Germline pathogenic variants in CDKN2A are well established as an underlying cause of familial malignant melanoma. While pathogenic
Gjertrud T. Iversen, Marie Loeng, Amalie Lund Holth, Per E. Lønning, Jürgen Geisler, Stian Knappskog   +5 more
wiley   +1 more source

Language as a Social and Political Factor in Europe [PDF]

, 1946
Maurice Bruce
openalex   +1 more source

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

Molecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu, Dilara Demirci, Sude Eris, Bengisu Dayanc, Ece Cakiroglu, Merve Basol, Merve Uysal, Gulcin Cakan‐Akdogan, Fang Liu, Mehmet Ozturk, Gökhan Karakülah, Serif Senturk   +11 more
wiley   +1 more source

Europe

, 2023
Bednar-Friedl B., R. Biesbroek, D. N. Schmidt, P. Alexander, K. Y. Børsheim, J. Carnicer, E. Georgopoulou, M. Haasnoot, G. Le Cozannet, P. Lionello, O. Lipka, C. Möllmann, V. Muccione, T. Mustonen, D. Piepenburg, L. Whitmarsh, Magnus Benzie, Pam Berry, Sara Burbi, Erika Coppola, Mladen Domazet, Frank Ewert, Federica Gasbarro, Matthias Gauly, François Gemenne, Peter Greve, Ana Iglesias, Elizabeth Kendon, Heidi Kreibich, Nikos Koutsias, Anna Laine- Petäjäkangas, Dimitris Lalas, Cristina Linares Gil, Danijela Markovic, Sadie McEvoy, Ana Mijic, Raya Muttarak, Rita Nogherotto, Hans Orru, Mark Parrington, Jeff Price, Kaisa Raitio, Marta Guadalupe Rivera Ferre, Jan C. Semenza, Rubén Valbuena, Michelle van Vliet, Heidi Webber, Laura Wendling, Katherine Yates, Monika Zurek   +49 more
openaire   +1 more source

Cultivating Europe: Democratic Europe - Social Europe - Educated Europe [PDF]

Proceedings of the Conference "Impact of Social Sciences and Humanities for a European Research Agenda - Valuation of SSH in mission-oriented research" VIENNA 2018, 2019
Kristina Wege, Geny Piotti, Stefanie Preuss, Nicole Birkle, Ursula Schichter, Christian Veldman, Katharina Berghöfer   +6 more
openaire   +2 more sources

The Orient and Europe* [PDF]

, 1938
V. Gordon Childe
openalex   +1 more source

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

Molecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit, Thais Pereira‐Veiga, Helena Brauer, Michael Horn, Paula Nissen, Thomas Mair, Bente Siebels, Hannah Voß, Ruimeng Zhuang, Marie‐Therese Haider, Desiree Loreth, Margarita Iskhakova, Bele Lindemann, Julian Kött, Laure Cayrefourcq, Jasmin Wellbrock, Hartmut Schlüter, Klaus Pantel, Catherine Alix‐Panabières, Manfred Jücker   +19 more
wiley   +1 more source