Results 191 to 200 of about 5,879,476 (365)
Protecting the mental health of youth
The Lancet Regional Health– Europe
doaj
The Global Game has changed: What Role for Europe-Africa Relations? [PDF]
This publication approaches some of the issues involved in the reshaping of EU-Africa relations in the recent past and for the next few years. Several authors, from Europe and from Africa, assess the partnership’s achievements so far and also the ...
Europe Africa Research Network
core
We investigated a potential protective effect of acacetin, a naturally occurring flavonoid, against methylglyoxal (MGO)‐induced endothelial dysfunction in human umbilical vein endothelial cells and its mechanism of action. Acacetin can could inhibit MGO‐induced intracellular calcium ion influx, enhance the expression levels of phosphorylated ...
Zhen Zhang+7 more
wiley +1 more source
The Vaccinated and unvaccinated need to coexist with tolerance and respect
The Lancet Regional Health – Europe
doaj
This study reports the upregulation of ELMO1 and GPR141 in human Fuchs' endothelial corneal dystrophy (FECD) corneal endothelium and ultraviolet A‐induced FECD mice model. A genetic association of an intergenic single nucleotide polymorphism rs918980 present between both genes is observed with FECD in the Indian population.
Susmita Sharma+3 more
wiley +1 more source
Enhancing foundation models for scientific discovery via multimodal knowledge graph representations
Foundation Models (FMs) hold transformative potential to accelerate scientific discovery, yet reaching their full capacity in complex, highly multimodal domains such as genomics, drug discovery, and materials science requires a deeper consideration of ...
Vanessa Lopez+8 more
doaj
Heavy metals and nitrogen in mosses: spatial patterns in 2010/2011 and long-term temporal trends in Europe [PDF]
Naturally-occurring mosses have been sampled across Europe to monitor the deposition of heavy metals and nitrogen from the air. This survey has been repeated at five-yearly intervals since 1990 for heavy metals and since 2005 for nitrogen.
Harmens, Harry+2 more
core
We introduce an immunohistochemistry method to measure autophagy flux, highlighting the active degradation and recycling of cellular waste. This cost‐effective approach uses tissue samples to track key markers like LC3 and SQSTM1, revealing how cells maintain health or respond to diseases such as cancer. It bridges the gap between research and clinical
Shahla Shojaei+6 more
wiley +1 more source
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik+3 more
wiley +1 more source
We generated and characterized clear cell renal cell carcinoma models using the patient‐derived RCC243 cell line—including cell culture, orthotopic, and metastatic tumors—via single‐cell RNA‐sequencing for comparisons between models and patient tumor datasets.
Richard Huang+9 more
wiley +1 more source