Results 51 to 60 of about 734,641 (266)

The effect of forest cover changes on the regional climate conditions in Europe during the period 1986–2015 [PDF]

open access: yesBiogeosciences
Afforestation affects the earth's climate system by changing the biogeochemical and biogeophysical characteristics of the land surface. While the regional effects of afforestation are well understood in the tropics and the high latitudes, its climate ...
M. Breil   +2 more
doaj   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

open access: yesMolecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal   +4 more
wiley   +1 more source

Between Political Nation and Ethnic‑Cultural Nation: Nations in Central Europe in the 20th Century

open access: yesPoliteja, 2018
The article analyzes the nation‑building process in Central Europe in the context of conditions and specific character of historical processes. It identifies the origin of the dilemma in Central Europe: political or ethnic‑cultural nations.
Waldemar Paruch
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Offender supervision in Europe: General trends and Serbian experience [PDF]

open access: yesNBP: Nauka, bezbednost, policija, 2014
Offender supervision represents an important mechanism applied during the execution of criminal sanctions and measures, especially of community or alternative sanctions. Official reports of some European countries suggest that the application of offender
Želeskov-Đorić Jelena   +1 more
doaj  

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

open access: yesMolecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta   +10 more
wiley   +1 more source

IN MEMORIAM.

open access: yesRevista da Faculdade de Direito da Universidade Federal de Minas Gerais
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Andrew Drzemczewski, Dean Spielmann
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

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