Results 71 to 80 of about 734,641 (266)
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Klimaschwankungen und Grosswetterlagen in Mitteleuropa seit 1881 [PDF]
Geographica HelveticaThe present paper is an attempt to contribute to the research of historical climatology of Central Europe. The representation and working out of the spatial and temporal differentiation of the secular variations in temperature occurring in Central ...
J. Grabau
doaj +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
, 2011 How much money is donated to nonprofit organizations in Europe? What’s the most generous country in the world? Very simple and interesting questions indeed. A radio listener commenting on our new estimates of the total amount donated by households in the Netherlands asked them. You would expect that there are data available answer them.
openaire +1 more source
Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
FEBS Open Bio, EarlyView.We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source
THE SPECIFIC MARKET RESEARCH METHODOLOGY USED AT GENERAL MOTOR'S EUROPE , [PDF]
Annals of the University of Oradea: Economic Science, 2011 As difficult as segmenting consumer markets is, it is much simpler and easier than segmenting industrial markets. Often the same industrial products have multiple applications; likewise, several different products can be used in the same application ...
Zima Liliana Adela, Toadere Rita Monica
doaj
BOOK REVIEW - Dominique WOLTON, Vive l’incommunication. La victoire de l’Europe [PDF]
Eastern Journal of European Studies, 2020 Dominique Wolton, in his latest book, explains that misunderstandings and misinterpretations between Europeans constitute a strength, not a weakness, for the construction of Europe, for the future of Europe. It is, in the end, a “Victory of Europe”.
Gilles ROUET
doaj
Inhibition of Classical and Alternative Complement Pathway by Ravulizumab and Eculizumab
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To explore the feasibility of classical (CH50) and alternative (AH50) complement pathway activity as potential biomarkers for treatment guidance and monitoring during therapy with ravulizumab in patients with generalized myasthenia gravis (gMG) and compare these to therapeutic drug monitoring under eculizumab.
Lea Gerischer +14 more
wiley +1 more source
GENERATIONAL SOLIDARITY IN EUROPE [PDF]
Innovation in Aging, 2017 A. Tur-Sinai +3 more
openaire +1 more source
Exploratory Analysis of ELP1 Expression in Whole Blood From Patients With Familial Dysautonomia
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Familial dysautonomia (FD) is a hereditary neurodevelopmental disorder caused by aberrant splicing of the ELP1 gene, leading to a tissue‐specific reduction in ELP1 protein expression. Preclinical models indicate that increasing ELP1 levels can mitigate disease manifestations.
Alejandra González‐Duarte +13 more
wiley +1 more source