Early‐stage health technology assessment of a curative gene therapy for multiple sclerosis
Aims Multiple sclerosis (MS) is associated with significant early morbidity, reduced life expectancy and substantial healthcare and societal costs. The primary objective of this study is to assess the early cost‐effectiveness potential of a novel gene therapy, IMMUTOL, for MS compared with current high‐efficacy treatment sequences.
Attila Imre, Balázs Nagy, Rok Hren
wiley +1 more source
Vitamin D and oral disease relationships: Insights from a bidirectional Mendelian randomization investigation. [PDF]
Shi Y, Li X, Chen B, Wang Y, Bai G.
europepmc +1 more source
Bjorn Kleizen, J. Wynen, Veronica Junjan
semanticscholar +1 more source
Cost–benefit analysis of screening programme for diabetic retinopathy in Bulgaria
Aims Late‐diagnosed diabetic retinopathy (DR) is difficult and expensive to treat. Screening programmes can identify the disease early and reduce the costs of its future treatment. This study aims to analyse the cost–benefit of screening programmes for DR.
Iva Nenkova +5 more
wiley +1 more source
Association between programmed electrical stimulation inducibility and arrhythmic risk in hypertrophic cardiomyopathy: a systematic review and meta-analysis. [PDF]
Salihu A +5 more
europepmc +1 more source
Aim Elexacaftor/tezacaftor/ivacaftor (ETI) has markedly improved cystic fibrosis (CF) outcomes. However, its long‐term impact on nutrition, metabolism and liver health remains underexplored. We assessed 30‐month changes in pulmonary, nutritional, metabolic and inflammatory markers in people with CF (PwCF) homozygous for F508del.
Nicola Perrotta +5 more
wiley +1 more source
Emergency medical services, treatment of cardiac arrest patients and cardiac arrest registries in Europe - Update on systems. [PDF]
Strömsöe A +2 more
europepmc +1 more source
EUROPEAN ARREST WARRANT IN THE SYSTEM OF LAW ENFORCEMENT ACTIVITIES
S. Davydenko, D.I. Demchenko
semanticscholar +1 more source
Buffalo chest after minimally invasive repair of pectus excavatum for pectus excavatum: results of the Chest Wall International Group (CWIG) survey. [PDF]
Donati F +3 more
europepmc +1 more source
Private Defence and Public Defence in the Criminal Law and in the Law of Tort—A Comparison'. [PDF]
Andoh, Benjamin, Parsons, Simon
core +2 more sources

