Results 91 to 100 of about 632,939 (308)

European Environmental Law and the Constitution [PDF]

open access: yes, 2003
The author describes how the European Union sought to institute environmental protection through the development of the constitution and the rights it guarantees such as the right to a healthy ...
Kiss, Alexandre
core   +2 more sources

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Article 93 as a European clause in the Spanish Constitution

open access: yesEastern European Journal of Transnational Relations
The purpose of this article is to answer the question of the legal nature of the European clause contained in the Spanish Constitution. The article examines how it has influenced the process of European integration and the constitutional order in that ...
Andrzej Jackiewicz
doaj   +1 more source

The Strengthening of the Commission Competences by the Constitutional Treaty and the Principle of Balance of Power [PDF]

open access: yes
A lot has been written about the European Commission as the main administrative institution of the European Community: about its work, competences, its organisational problems and the administrative reform initiated by President Prodi after the ...
Eva Nieto Garrido
core  

Which constitution for what kind of Europe? [PDF]

open access: yes, 2003
Discussion of the pros and cons of an EU constitution tends to focus upon two issues. On the one hand, proponents and opponents of reform seek to legitimate the EU as a 'regime', or form of governance.
Bellamy, R.
core  

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

open access: yesFEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani   +6 more
wiley   +1 more source

CIVIC PARTICIPATION-ELEMENT OF EUROPEAN DEMOCRACY [PDF]

open access: yes
Democracy is explained by giving the power to the government, with the consent of citizens, expressing their will, directly or indirectly through voting.
Ana-Maria Bercu
core  

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

open access: yesFEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold   +11 more
wiley   +1 more source

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