Results 61 to 70 of about 632,494 (309)

Democracy and rule of law: the Hungarian goulash [PDF]

, 2013
The article discusses the Tavares Report on the new constitutional changes in Hungary, the implications of the new Constitution on Hungary's obligation under the Treaty, on European Union, especially its continuing commitment to the Union founding ...
Ressel, James
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Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Remapping the European Cultural Memory: The Case of Julia Kristeva’s \u3cem\u3eMurder in Byzantium\u3c/em\u3e [PDF]

, 2010
This article considers Julia Kristeva’s novel Murder in Byzantium in the context of some of the most pressing ehtical and political dilemmas faced by Europe today, regarding the role of religion and the inclusion of religious references in the ...
Rus, Bianca Laura
core   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Ideology, constitutional culture and institutional change: the EU constitution as reflection of Europe’s emergent postmodernism [PDF]

Using the example of the European Constitution, this paper argues that ideology plays a much more important role in institutional change than has been indicated hitherto in the literature.
Nikolay Wenzel
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The European Constitution: past and future [PDF]

, 2003
Does Europe need a Constitution? This is the question that has attracted the attention of observers of the European scene, especially lawyers and political scientists, ever since the debate over Giscard d'Estaing's draft Constitution revived public ...
Puig, Gonzalo Villalta
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Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Representation in International Relations, Impeachment of the President of Georgia, and European Integration

TalTech Journal of European Studies
The 2017–2018 constitutional reform amended the Constitution of Georgia and changed the political system of the country. The president has the responsibility to represent the country in international relations, but only with the approval of the ...
Gegenava Dimitry, Goradze George
doaj   +1 more source

For a European Constitutional Patriotism

Political Studies, 2002
In recent years, two dominant models for understanding the source of common political identities have emerged in the European context: the universalist paradigm of constitutional patriotism and the communitarian paradigm of ‘civic nationalism’. In view of this dichotomy, one could be tempted to think that only a combination of these two positions ...
openaire   +2 more sources

The European Constitution Project from the Perspective of Constitutional Political Economy [PDF]

Three topics of a European constitution are discussed. First, basic arguments from constitutional political economy that aim at restricting representatives’ potential misuse of powers in a European Union with extended competencies are summarized. Since a
Lars P. Feld
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