Results 81 to 90 of about 632,939 (308)

From Austerity to Solidarity: How Deviations Preserve the EU’s Macro-Constitution

European Constitutional Law Review
Treaties of the European Union – Comprehensive framework for macro-economic governance, devoid of democratic influence – Divergence from this seemingly stringent framework during the Euro Crisis and the Covid-19 pandemic – Pattern of deviation from the ...
Hilary Hogan
doaj   +1 more source

The European Constitutional Settlement [PDF]

The World Economy, 2007
This paper argues first that a synthesis of the theories of endogenous policy formation, non‐coercive interstate bargaining theory, and international regime theory provides a plausible account of the path of European integration, with little role for explanations stressing geopolitical or ideological factors, international mediation, or political ...
openaire   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Europejska filozofia praw człowieka a konstytucyjna formuła obowiązków człowieka i obywatela

Filozofia Publiczna i Edukacja Demokratyczna, 2018
This article is devoted to the problem of the obligations of a human and citizen in the Polish constitution. This matter is shown from the philosophy and legal point of you.
Bartosz Liżewski
doaj   +1 more source

The Importance of Being Nice: An Institutionalist Analysis of French Preferences on the Future of Europe [PDF]

This article offers an institutionalist explanation of French preferences on the future of Europe from the Maastricht Treaty of 1992 through the Constitutional Treaty of 2004. It argues that the autonomous institutional logic of the constitution-drafting
Nicolas Jabko
core  

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

"Decision Making in Europe: Were Spain and Poland Right to Stop the Constitution in December 2003?" [PDF]

, 2005
This paper tries to explain why Spain and Poland stopped the Draft Constitution for the European Union in December 2003 and discusses whether this action was compatible with these countries long term interests. The author finds that the decline in power –
Ade, Florian.
core  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

The Economics of Discrimination: Equity, Equality and Diversity in the New European Constitution [PDF]

This chapter reviews some aspects of the new draft constitution for the European Union, pointing to possible undesirable consequences from including non-discrimination as a general rule in the European constitution.
Giancarlo Corsetti, Gilles Saint-Paul, Hans-Werner Sinn, John Kay, Lars Calmfors, Seppo Honkapohja, Willi Leibfritz, Xavier Vives   +7 more
core  

The European Union in Transition: The Treaty of Nice in Effect; Enlargement in Sight; A Constitution in Doubt [PDF]

, 2003
This Article is intended to provide an overview of this transitional moment in the history of the European Union. Initially, the Article will briefly review the background of the Treaty of Nice, and the institutional structure modifications for which it ...
Goebel, Roger J.
core   +1 more source