Results 51 to 60 of about 5,647,471 (345)
Aggressive prostate cancer is associated with pericyte dysfunction
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Status of the “Nord Stream” according to European Union Law
In 2000, the European Commission has recognized, passing through the Baltic Sea «Nord Stream» project part of the Trans-European energy network. In September 2006, the Commission stated that it was one of the energy projects of the highest priority of ...
Moskwa Urszula
doaj +1 more source
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
WLCG Authorisation from X.509 to Tokens [PDF]
The WLCG Authorisation Working Group was formed in July 2017 with the objective to understand and meet the needs of a future-looking Authentication and Authorisation Infrastructure (AAI) for WLCG experiments. Much has changed since the early 2000s when X.
Bockelman Brian +12 more
doaj +1 more source
Next‐generation proteomics improves lung cancer risk prediction
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
El terme ciberterrorisme salta a la llum pública en grans titulars periodístics a finals del segle passat i principis del present, particularment, a partir dels atemptats de l'11-S a Nova York.
Alicia Chicharro Lázaro
doaj +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
The European Parliament : leadership and 'followership' [PDF]
The weakened European Commission and the increasingly assertive European Council and Council of Ministers have contended for control of agenda-setting but it is in the sphere of foreign and security policy that the EU's logic of leaderlessness has been ...
Earnshaw, David, Judge, David
core
Impact of ocean warming on sustainable fisheries management informs the Ecosystem Approach to Fisheries [PDF]
Acknowledgements Serpetti N., Heymans J.J., and Burrows M.T. were funded by the Natural Environment Research Council and Department for Environment, Food and Rural Affairs under the Marine Ecosystems Research Programme (MERP) (grant No.
Baudron, Alan R +6 more
core +2 more sources
European Resuscitation Council Guidelines 2021: Education for resuscitation.
These European Resuscitation Council education guidelines, are based on the 2020 International Consensus on Cardiopulmonary Resuscitation Science with Treatment Recommendations. This section provides guidance to citizens and healthcare professionals with
R. Greif +12 more
semanticscholar +1 more source

