Results 61 to 70 of about 5,647,471 (345)

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Principis deontològics dels professionals de la informació i la documentació : el codi de l'European Council of Information Association (ECIA)

BiD: Textos Universitaris de Biblioteconomia i Documentació, 2001
Codi deontològic acordat per l'European Council of Information Associations al 1999, per tal que servís per als professionals de la informació dels països de la Unió Europea.
European Council of Information Associations
doaj  

Which Messages about Healthy and Sustainable Eating Resonate Best with Consumers of Low Socio-Economic Status?

Proceedings
Consumers of low socio-economic status (SES) face unique challenges in eating healthily and sustainably, and as a result, are disproportionately affected by the greater risks of chronic diseases and environmental degradation.
Aikaterini Palascha, Betty Chang, Nina McGrath   +2 more
doaj   +1 more source

From sanctions to summits: Belarus after the Ukraine crisis [PDF]

, 2015
Belarus is concerned by Russian actions in Ukraine and is trying to distance itself from Russia, including by not recognising the annexation of Crimea and calling for a peacekeeping mission. It is also suffering the effects of Russia’s economic downturn.
European Council on Foreign Relations, Kryvoi, Yaraslau, Wilson, Andrew   +2 more
core  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Interpretazione dei Trattati istitutivi dell'UE: quale ruolo per le decisioni assunte in sede di Consiglio europeo?

European Papers, 2016
(Series Information) European Papers - A Journal on Law and Integration, 2016 1(1), 177-184 | European Forum Insight of 16 April 2016 | (Table of Contents) I. Introduzione. - II.
Giulia D'Agnone
doaj   +1 more source

Evolution of Th2 responses : Characterization of IL-4/13 in sea bass (Dicentrarchus labrax L.) and studies of expression and biological activity [PDF]

, 2017
Acknowledgements This research was funded by the European Commission under the 7th Framework Programme for Research and Technological Development (FP7) of the European Union (Grant Agreement 311993 TARGETFISH). T.W.
A Antczak, A Bhattacharjee, A Munitz, AE Lockyer, E Wangkahart, EJ Song, F Buonocore, F Takizawa, G Biswas, G Scapigliati, H Nielsen, J Zhu, J Zou, JE Allen, JH Li, JW Hodgkinson, K Bao, K Tamura, L-y Zhu, LM Braden, M Howard, M Ohtani, M Tine, M Wills-Karp, MG Reese, MM Costa, MO Huising, N Nunez Ortiz, PJ Lupardus, RC Edgar, RL Coffman, S Almeria, S Kumar, S McCormick, SP Gadani, T Hage, T Maehr, T Wang, T Wang, T Wang, T Wang, T Yamaguchi, T Yamaguchi, TA Wynn, TA Wynn   +44 more
core   +1 more source

European Resuscitation Council Guidelines 2021: Systems saving lives.

Resuscitation, 2021
The European Resuscitation Council (ERC) has produced these Systems Saving Lives guidelines, which are based on the 2020 International Consensus on Cardiopulmonary Resuscitation Science with Treatment Recommendations.
F. Semeraro, R. Greif, B. Böttiger, R. Burkart, D. Cimpoesu, M. Georgiou, J. Yeung, F. Lippert, Andrew S Lockey, T. Olasveengen, G. Ristagno, J. Schlieber, S. Schnaubelt, A. Scapigliati, Koenraad G Monsieurs   +14 more
semanticscholar   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Positions of the Leading European Parties on the Eve of the European Parliament Elections 2024 [PDF]

Современная Европа
The article analyses the main trends in the transformation of the party and political system of the European Union on the eve of the next elections to the European Parliament in June 2024. The article examines the main events of recent years that had the
Boris P. Guseletov
doaj   +1 more source