Results 31 to 40 of about 521,257 (307)

Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende, Emilien Petit, Young Woo Park, Sophie Tezenas du Montcel, James M. Joers, Jonathan M. DuBois, H. Moore Arnold, Michal Povazan, Ipek Özdemir, Guita Banan, Romain Valabregue, Philipp Ehses, Jennifer Faber, Chiadi U. Onyike, Peter B. Barker, Jeremy D. Schmahmann, Eva‐Maria Ratai, Sub H. Subramony, Thomas H. Mareci, Khalaf O. Bushara, Henry Paulson, Thomas Klockgether, Alexandra Durr, Tetsuo Ashizawa, Christophe Lenglet, Gülin Öz, READISCA Investigators   +26 more
wiley   +1 more source

International Order, Political Community, and the Search for a Eurpoean Public Philosophy [PDF]

, 1998
The shaping of international order, and the place of concepts such as law and community within that order, has emerged as one of the most pressing issues in contemporary legal and political thought.
Ward, Ian
core   +1 more source

Cracking the Code: Which Ocular Symptoms Predict Dry Eye Signs? Insights from a large international sicca registry

Arthritis Care &Research, Accepted Article.
Purpose The study aimed to identify symptom‐based predictors of dry eye disease (DED) signs in the Sjögrens International Collaborative Clinical Alliance (SICCA) cohort. Methods Retrospective analysis examining 16 ocular symptoms (most graded 0‐4) and artificial tear (AT) use (graded 0‐3) as predictors of DED signs [abnormal ocular surface staining ...
Pragnya R Donthineni, Chloe Shields, Rohit Muralidhar, Shreya Bhatt, Alan Baer, Robert Fox, Sara S. McCoy, Anat Galor   +7 more
wiley   +1 more source

Emergence and Development of the Foreign Political Dimension of the EU: PreMaastricht Period

Європейські історичні студії, 2017
Almost from the very outset the development of the common foreign policy and establishing the common defense have been the main aims of the European Community, but the real cooperation in these fields turned out to be quite complex and run into certain ...
Victoria Ruda
doaj   +1 more source

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

Advanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa, Gracia Mendoza, Silvia Irusta, Manuel Arruebo   +3 more
wiley   +1 more source

The External Relations of the European Union towards the United States: How Relevant is the European Union in Constraining or Replacing U.S. Hegemony?, Jean Monnet/Robert Schuman Paper Series, Vol. 1 No. 3, September 2002 [PDF]

, 2002
(From the introduction). The study object of this paper is the external relations of the European Union towards the United States. The core question of this essay is not the U.S.
Rivera, Roberto Domínguez.
core  

Mesoporous Silica Nanoparticles in Biomedicine: Advances and Prospects

Advanced Materials, EarlyView.
Mesoporous silica nanoparticles offer unique properties like high surface area, tunable pores, and functionalization. They excel in drug delivery, tissue engineering, and stimuli‐responsive therapies, enabling targeted and controlled treatments. With roles in cancer therapy and diagnostics, their clinical translation requires addressing challenges in ...
Miguel Manzano, María Vallet‐Regí
wiley   +1 more source

Identification of sources of formation of the State Budget of Ukraine and directions of use of financial resources in the context of the russian-Ukrainian war

Економіка, управління та адміністрування
The article analyzes the sources of financial revenues to the State Budget of Ukraine and the use of financial resources in the context of the russian-Ukrainian war. The changes in the structure of revenues were investigated.
O.S. Dyka
doaj   +1 more source

Metatranscriptomics From a Small Aquatic System: Microeukaryotic Community Functions Through the Diurnal Cycle

Frontiers in Microbiology, 2020
Light is an important factor for the growth of planktonic organisms, and many of them depend on the diurnal light/dark cycle to regulate key metabolic processes.
Stephanie Trench-Fiol, Patrick Fink, Patrick Fink, Patrick Fink   +3 more
doaj   +1 more source

Legal regulation of national security in Ukraine: today’s challenges

Law and Safety, 2022
The article is devoted to the study of the legal regulation of national security in Ukraine. Against the background of the full-scale invasion of Russia on the territory of Ukraine, this issue becomes particularly relevant and requires a more detailed ...
Ye. V. Kobko
doaj   +1 more source