Results 101 to 110 of about 1,080,560 (314)

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

The Price of Ethics: Evidence from Socially Responsible Mutual Funds [PDF]

open access: yes
This paper estimates the price of ethics by studying the risk-return relation in socially responsible investment (SRI) funds. Consistent with investors paying a price for ethics, SRI funds in many European and Asia-Pacific countries strongly underperform
Horst, J.R. ter   +2 more
core   +4 more sources

Regional devolopment and solidarity in Spain: the relationship between the E.C. and the internal solidarity funds. [PDF]

open access: yes
This paper will analyse the importance that the Regional Solidarity Funds have acquired in the financial systems of those Autonomous Communities able to benefit from them, and the influence that these Funds have had in their development. In addition, the
Ana Isabel González   +2 more
core  

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Audit of European Funds Destined to the Development of Agricultural Sector [PDF]

open access: yesOvidius University Annals: Economic Sciences Series, 2018
Romania has benefited until now by European funds destined to the development of agriculturalsector and rural environment during two periods of time: pre-adherence period 2000-2006 whenfunds were accessed through SAPARD program and the post- adherence ...
Vârteiu Daniel Petru
doaj  

Between development and social policies: the impact of European Structural Funds in Objective 1 Regions [PDF]

open access: yes
European regional support has grown in parallel with European integration. The funds targeted at achieving greater economic and social cohesion and reducing disparities within the European Union (EU) have more than doubled in relative terms since the end
Andrés Rodríguez-Pose, Ugo Fratesi
core  

EUROPEAN FUNDS HELP ROMANIAN AGRICULTURE

open access: yesWorld Science, 2020
The EU Structural Funds are managed by the European Commission and are intended to finance structural assistance measures at Community level, with the aim of promoting regions with developmental delays, reconverting areas affected by industrial decline, combating long-term unemployment, employing young people or promoting rural development.
openaire   +3 more sources

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

THE ANALYSIS OF ABSORPTION CAPACITY OF EUROPEAN FUNDING IN THE NORTH WESTERN REGION OF ROMANIA [PDF]

open access: yesAnnals of the University of Oradea: Economic Science, 2010
This paper analyzes the Romanian absorption capacity of the funds allocated through the REGIO programme, which is part of ERDF programme. Within the paper are presented the concept of absorption capacity and several opinions regarding its main composing ...
Droj Laurentiu
doaj  

PHILOSOPHY AND METHODS OF EXAMINING THE IMPACT OF THE EUROPEAN REGIONAL POLICY [PDF]

open access: yes
It is a very generally accepted view that financial support received from the European Union generates a large growth surplus. The potential effects of the structural funds calculated in model simulations carried out by the European Commission support ...
Tron Zsuzsanna
core  

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