Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky +8 more
wiley +1 more source
New Frontiers of European Union Funding
Abstract European Union (EU) funding has been characterized by significant innovations since 2020, and these often controversial innovations give rise to complex legal issues. It is time for legal scholars to join other political and social scientists in trying to make sense of these innovations.
KILPATRICK, Claire, SCOTT, Joanne
openaire +2 more sources
Innovation policy in the European Union: instruments and objectives [PDF]
We provide an overview of the specific innovation policies that are implemented at European level, highlighting, where possibile, the connections between these policies and the guidance documents issued by the Community’s institutions.
Rossi, Federica
core +1 more source
Cutaneous Phosphorylated Alpha‐Synuclein in Lewy Body Dementia
ABSTRACT Objective To determine the test performance of cutaneous phosphorylated alpha‐synuclein (P‐SYN) in dementia with Lewy bodies (DLB), individuals with reduced Montreal Cognitive Assessment (MoCA) and healthy controls. Methods This is the first subgroup analysis of the Synuclein‐One study, a prospective, blinded study evaluating P‐SYN detection ...
Christopher H. Gibbons +31 more
wiley +1 more source
ROMANIAN RURAL DEVELOPMENT AND THE FINANCING POLICY [PDF]
Romania has a large rural areas and a great potential, but the Romanian rural has many economic and social issues. The main idea is that the major risk for the Romanian rural development is generated of the combination between the transition problems ...
Assoc. Prof. Laura Giurcă Vasilescu Ph. D. +1 more
core
Shared Genetic Effects and Antagonistic Pleiotropy Between Multiple Sclerosis and Common Cancers
ABSTRACT Objective Epidemiologic studies have reported inconsistent altered cancer risk in individuals with multiple sclerosis (MS). Factors such as immune dysregulation, comorbidities, and disease‐modifying therapies may contribute to this variability.
Asli Buyukkurt +5 more
wiley +1 more source
Intelligent Region Management = Intelligent Absorption of EU funds [PDF]
Effective institutions and public administration is a key factor in designing and implementing the growth policy and the economic and social development.
Cornelius Pylak
core
Immune‐Driven Expression in Inclusion Body Myositis With T‐Cell Large Granular Lymphocytic Leukemia
ABSTRACT Objectives T‐cell large granular lymphocytic leukemia (T‐LGLL), reported in up to 58% of inclusion body myositis (IBM) patients, is a rare leukemia of cytotoxic or less commonly helper T cells. The range of myopathies in T‐LGLL and the impact of coexisting T‐LGLL in IBM are not well understood. Our objectives are to investigate the spectrum of
Pannathat Soontrapa +10 more
wiley +1 more source
THE EUROPEAN FUNDS – AN ANTI-CRISIS MEASURE AT THE MOMENT [PDF]
The European funds do not represent an inward purpose, but instruments in reaching the objectives established at the level of the European Union, of the EU member state, based on the implementation documents.
Daniela Florescu
core
Whole‐Body Pattern of Muscle Degeneration and Progression in Sarcoglycanopathies
ABSTRACT Objective To characterize whole‐body intramuscular fat distribution pattern in patients with sarcoglycanopathies and explore correlations with disease severity, duration and age at onset. Methods Retrospective, cross‐sectional, multicentric study enrolling patients with variants in one of the four sarcoglycan genes who underwent whole‐body ...
Laura Costa‐Comellas +39 more
wiley +1 more source

