Results 111 to 120 of about 5,721,607 (198)

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

open access: yesMolecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira   +7 more
wiley   +1 more source

European Money at Work: Contracting a European Identity? [PDF]

open access: yes
Most literature on the interaction between European institutions and NGOs focuses on interest representation and lobbying. This article tackles a neglected aspect of this interaction: the effects of European funding opportunities on NGO's organizational ...
Rosa Sanchez Salgado
core  

"United in Diversity": The Church's Experience and the European Union's Identity Motto. European Diversity and Autonomy Papers. EDAP 2/2008 [PDF]

open access: yes, 2008
The paper analyses a potential relationship between religion and politics in the context of the EU’s motto, unity in diversity. It’s aimed at verifying the thesis that claims the European Union’s identity motto has its roots in the ecclesial model of ...
Gierycz, Michal.
core  

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

open access: yesMolecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico   +5 more
wiley   +1 more source

How European Do Young Slovenians Feel?

open access: yesPolitics and Governance
The last two decades of European integration have been challenging for European identity for various reasons. First, the 2004 and subsequent enlargement (in 2007 and 2013) of the EU to Central and Eastern Europe have further extended the diversity of the
Meta Novak, Damjan Lajh
doaj   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth   +17 more
wiley   +1 more source

The Permeability of Social Boundaries for Russians in the Post-Soviet Space: The Role of Social Identities and Perceived Security

open access: yesRUDN Journal of Psychology and Pedagogics
Russians are one of the largest ethnocultural minorities in the post-Soviet and the issue of their inclusion in the societies of host countries remains relevant.
Maria A. Bultseva   +2 more
doaj   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

Why Is it so Difficult to Know if National Pride Leads the Way to European Identity or Prevents it ? [PDF]

open access: yes
For a long time, support for European integration could be analysed without much reference tothe attachments of European citizens to their nations.
Sophie Duchesne, André-Paul Frognier
core  

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

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